Managing Hematuria in Dialysis Patients with Polycystic Kidney Disease - Urology

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Patients with polycystic kidney disease on dialysis may experience hematuria?


Hello Doctor: I am a dialysis patient with polycystic kidney disease.
Recently, for the past two weeks, I have been experiencing hematuria, with the blood appearing dark brownish-red.
I do not have a fever or body aches.
The dialysis center has administered hemostatic injections, and the amount of blood in my urine has decreased over the past few days.
Should I go to the hospital for an invasive urethral examination, or could it be that a cyst has ruptured and the bleeding will resolve on its own?

Ya Liang, 40~49 year old female. Ask Date: 2018/02/22

Dr. Chen Jiansheng reply Urology


Patients undergoing dialysis who present with hematuria may be affected not only by anticoagulants administered during the procedure but also by other factors such as stones, polyps, tumors, or infections.
It is recommended to consult a urologist for a thorough examination.

Reply Date: 2018/02/22

More Info


Managing hematuria, or blood in the urine, in patients with polycystic kidney disease (PKD) who are on dialysis can be complex and requires careful evaluation. Given your situation, where you have experienced dark red-brown hematuria without fever or body aches, it is crucial to consider several factors before deciding on further invasive procedures.

Firstly, it is important to understand that hematuria in dialysis patients, particularly those with PKD, can arise from various causes. In your case, the presence of cysts in the kidneys can lead to complications such as cyst rupture, which may cause bleeding. Other potential causes of hematuria in this context include urinary tract infections, kidney stones, or even malignancies, although the latter is less common in younger patients.

The fact that you have received a hemostatic injection at your dialysis center and noticed a reduction in the volume of blood in your urine is a positive sign. This suggests that the bleeding may have been controlled, at least temporarily. However, it does not eliminate the need for further investigation, especially if the hematuria persists or recurs.

In terms of whether you should undergo invasive procedures, such as cystoscopy (a procedure that allows a doctor to examine the bladder and urethra), it is essential to weigh the risks and benefits. Cystoscopy can provide direct visualization of the urinary tract and help identify the source of bleeding. However, in patients with PKD, there is a risk of exacerbating existing conditions, such as cyst rupture or infection.

Before proceeding with any invasive investigation, it is advisable to have a thorough evaluation by a urologist or nephrologist. They may recommend non-invasive imaging studies, such as a renal ultrasound or a CT scan, to assess the kidneys and urinary tract for any abnormalities, such as cyst enlargement or signs of infection. These imaging studies can often provide valuable information without the risks associated with invasive procedures.

If imaging studies indicate that the cysts are stable and there are no other concerning findings, conservative management may be appropriate. This could include close monitoring of your symptoms and urine output, as well as maintaining hydration and managing any underlying conditions that could contribute to hematuria.

In summary, while it is essential to investigate the cause of hematuria in patients with PKD on dialysis, the approach should be cautious. Non-invasive imaging studies are typically the first step, and invasive procedures should be reserved for cases where there is a clear indication of a significant problem that cannot be addressed through less invasive means. Always consult with your healthcare provider to determine the best course of action based on your specific circumstances and medical history.

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