Managing Hypertension: Concerns About Medication Side Effects and Dosage - Internal Medicine

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Antihypertensive medications


Hello, currently my medication regimen includes 1.
Olmesartan 40 mg in the morning and 2.
Bisoprolol 1.25 mg in the evening.
My blood pressure in the morning is generally below 120/80, but in the evening, it measures around 136/89 (after taking the medication).
Since starting the medication, I have been experiencing dizziness and tinnitus, which I have discussed with my doctor, but they said it is not caused by the medication.
The symptoms are particularly severe in the evening.
I am wondering if it would be possible to reduce the dosage? Thank you.

Mr. Li, 40~49 year old female. Ask Date: 2018/04/19

Dr. Hong Yuanbin reply Internal Medicine


Hello, based on your description, if your blood pressure remains at the values you mentioned, it is indeed advisable to use antihypertensive medication.
The medication you are currently using is commonly prescribed.
As for whether your symptoms are caused by the medication or if you should switch to another type, it is recommended that you have a detailed discussion with your physician.
Additionally, I suggest measuring your blood pressure 2-3 times a day and recording the readings, so you can show them to your attending physician during your next appointment.
This will help in adjusting your antihypertensive medication.
Thank you for your inquiry.

Reply Date: 2018/04/19

More Info


Managing hypertension effectively often involves a careful balance of medication, lifestyle changes, and monitoring for side effects. In your case, you are currently taking Olmesartan 40 mg in the morning and Bisoprolol 1.25 mg in the evening. Your blood pressure readings indicate that you are generally within an acceptable range during the day, but you experience higher readings at night, along with persistent symptoms of dizziness and tinnitus (ear ringing).


Understanding Your Medications
1. Olmesartan: This medication is an angiotensin II receptor blocker (ARB) that helps to relax blood vessels, thereby lowering blood pressure. It is effective for many patients and is generally well-tolerated. Side effects can include dizziness, headache, and in rare cases, kidney issues or elevated potassium levels.

2. Bisoprolol: This is a beta-blocker that reduces heart rate and the workload on the heart, which can also help lower blood pressure. Common side effects include fatigue, dizziness, and bradycardia (slow heart rate). It can also cause or exacerbate symptoms like dizziness and tinnitus, especially if the dosage is too high for your body’s tolerance.


Addressing Your Symptoms
The symptoms you are experiencing—dizziness and tinnitus—can be concerning, especially if they are persistent. While your doctor has indicated that these symptoms are not likely caused by your medications, it is essential to consider a few factors:
- Dosage: The current dosage of Bisoprolol may be too high for you, especially if you are experiencing significant side effects. Reducing the dosage could potentially alleviate your symptoms. However, any changes to medication should always be discussed with your healthcare provider before making adjustments.

- Timing of Medications: Taking Bisoprolol in the evening may lead to a drop in blood pressure during the night, which could explain the dizziness. Some patients may benefit from taking their beta-blocker in the morning instead. Again, this is something to discuss with your doctor.

- Blood Pressure Variability: It is not uncommon for blood pressure to fluctuate throughout the day. The readings you provided indicate that your blood pressure is slightly elevated at night. This could be due to various factors, including stress, fluid retention, or even the timing of your medications.


Lifestyle Considerations
In addition to medication management, lifestyle changes can significantly impact blood pressure control:
- Diet: A heart-healthy diet, such as the DASH (Dietary Approaches to Stop Hypertension) diet, emphasizes fruits, vegetables, whole grains, and lean proteins while reducing salt intake.

- Exercise: Regular physical activity can help lower blood pressure and improve overall cardiovascular health. Aim for at least 150 minutes of moderate aerobic activity each week.

- Stress Management: Techniques such as mindfulness, yoga, or deep-breathing exercises can help manage stress, which may contribute to blood pressure spikes.

- Regular Monitoring: Keep track of your blood pressure readings at different times of the day. This information can be valuable for your healthcare provider in assessing your treatment plan.


Conclusion
Given your current situation, it is crucial to have an open dialogue with your healthcare provider about your symptoms and concerns. If you feel that your symptoms are impacting your quality of life, do not hesitate to seek a second opinion or ask for a referral to a specialist, such as a cardiologist or a hypertension specialist. They can provide further evaluation and may suggest alternative treatment options or adjustments to your current regimen. Always prioritize your health and well-being, and ensure that any changes to your medication are made under professional guidance.

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