Proteinuria: What Your Health Check Results Mean - Internal Medicine

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Health check-up: Proteinuria


I have vasculitis and mild arrhythmia, and I am taking immunosuppressive medication, anti-inflammatory drugs, and anti-arrhythmic medication.
I recently had a check-up, but I couldn't understand the report as the doctor was in a hurry and told me to read it myself.

In my blood test, the white blood cell count was 10.4 (reference range: 4.0-9.8), while the other blood tests were normal.
Liver function tests showed S.G.O.T (22) with a reference range of 0-39, S.G.P.T (29) with a reference range of 0-41, r-GTP (104) with a reference range of 9-64, and ALK-P (83) with a reference range of 34-104.
Total bilirubin was (0.29) with a reference range of 0.20-1.00.
All hepatitis B and C tests were normal, and other liver function tests were normal as well.

Kidney function tests showed B.U.N (13) with a reference range of 7-25, creatinine (0.63) with a reference range of <1.3, and uric acid (5.1) with a reference range of 2.3-6.6.
In the urine test, there was proteinuria (+) with a reference range of (-), and the urine white blood cell count was 21-25 with a reference range of 0-6.
Bacteria were negative (reference range: -).
Triglycerides were 205 with a reference range of <150.

I am concerned about whether I have liver or kidney issues due to the proteinuria.

Zhang Xuanxuan, 20~29 year old female. Ask Date: 2018/04/18

Dr. Wu Hongjie reply Internal Medicine


If there are concerns about liver function, please consult a gastroenterologist.
Urine protein is 1+, and it is recommended to visit a nephrologist for further testing.
Wishing you good health and safety.

Reply Date: 2018/04/18

More Info


Understanding your health check results, especially when it comes to proteinuria and other related parameters, can be quite daunting. Let's break down your lab results and what they mean in the context of your health conditions, particularly considering your history of vasculitis and mild arrhythmia, as well as the medications you are taking.


Key Lab Results Breakdown
1. White Blood Cell Count (WBC): Your WBC count is 10.4 (normal range: 4.0-9.8). This slight elevation may indicate an inflammatory response, which could be related to your underlying conditions or medications. It's essential to monitor this, especially since you have a history of vasculitis.

2. Liver Function Tests:
- S.G.O.T (AST): 22 (normal range: 0-39)
- S.G.P.T (ALT): 29 (normal range: 0-41)
- r-GTP: 104 (normal range: 9-64)
- ALK-P: 83 (normal range: 34-104)
- Total Bilirubin: 0.29 (normal range: 0.20-1.00)
Your liver enzymes (AST and ALT) are within normal limits, which is a positive sign. However, the r-GTP level is elevated, which could suggest some liver stress or bile duct issues. It's crucial to discuss this with your healthcare provider, especially considering your medication regimen.

3. Kidney Function Tests:
- B.U.N: 13 (normal range: 7-25)
- Creatinine: 0.63 (normal range: <1.3)
Both B.U.N and creatinine levels are within normal ranges, indicating that your kidneys are functioning well. This is reassuring, especially since you have proteinuria.

4. Proteinuria: The presence of protein in your urine (indicated as positive) is a concern. Normal urine protein levels should be negative. Proteinuria can be a sign of kidney damage or disease, particularly in the context of systemic conditions like vasculitis. It’s essential to monitor this closely.

5. Urine White Blood Cells: Your urine shows 21-25 white blood cells (normal range: 0-6), which indicates inflammation or infection in the urinary tract. This could be related to your underlying conditions or a separate issue that needs to be addressed.

6. Triglycerides: Your triglyceride level is 205 (normal range: <150), which is elevated. High triglycerides can be a risk factor for cardiovascular disease, especially in individuals with arrhythmias.


Recommendations and Considerations
1. Follow-Up on Proteinuria: Given your proteinuria and elevated urine white blood cells, it’s crucial to follow up with your healthcare provider. They may recommend a 24-hour urine collection to quantify the protein and assess kidney function more accurately. This will help determine if the proteinuria is transient (possibly due to dehydration or exercise) or indicative of a more serious condition.

2. Monitor Liver Function: The elevated r-GTP should be monitored. Discuss with your doctor whether any adjustments to your medications are necessary, especially if they could be contributing to liver stress.

3. Manage Triglycerides: Since your triglyceride levels are elevated, consider dietary changes, such as reducing sugar and refined carbohydrates, increasing omega-3 fatty acids, and incorporating regular physical activity. Discuss with your healthcare provider if medication is needed to manage this.

4. Hydration and Diet: Ensure you are adequately hydrated, as dehydration can contribute to proteinuria. A balanced diet rich in fruits, vegetables, whole grains, and lean proteins can support overall health and kidney function.

5. Regular Monitoring: Given your history of vasculitis and arrhythmia, regular monitoring of your kidney function, liver enzymes, and overall health is essential. Keep an open line of communication with your healthcare provider about any new symptoms or concerns.

In summary, while some of your results are within normal ranges, the presence of proteinuria and elevated urine white blood cells warrants further investigation. It’s crucial to work closely with your healthcare provider to understand the implications of these results and to develop a management plan tailored to your health needs.

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