Can You Safely Combine Blood Pressure Medications with Viagra? - Cardiology

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Can medications be taken together?


I take blood pressure medication (Cozaar 50mg) once daily.
Is this medication classified as a nitrate? Can I also take Viagra? Will there be any interactions or side effects between the two medications? Thank you!

Tiansheng, 60~69 year old female. Ask Date: 2018/04/28

Dr. He Dongjin reply Cardiology


Hello, he is not taking nitrate medications, so it is safe to take Viagra without affecting him or causing side effects.
Changhua Hospital cares about you.

Reply Date: 2018/04/28

More Info


When considering the combination of blood pressure medications like Cozaar (losartan) with Viagra (sildenafil), it is essential to understand the pharmacological profiles of these drugs and their potential interactions. Cozaar is an angiotensin II receptor blocker (ARB) used primarily to treat high blood pressure and heart failure, while Viagra is a phosphodiesterase type 5 (PDE5) inhibitor used to treat erectile dysfunction.

Firstly, it is important to note that Cozaar is not classified as a nitrate or a nitroglycerin medication. Nitrates are typically contraindicated with PDE5 inhibitors like Viagra due to the risk of severe hypotension (low blood pressure). However, since Cozaar does not fall into this category, it can generally be used safely with Viagra.

The combination of Cozaar and Viagra does not typically lead to significant interactions. Studies have shown that sildenafil does not adversely affect the blood pressure-lowering effects of ARBs like Cozaar. In fact, some research suggests that sildenafil may even have a mild blood pressure-lowering effect on its own, which could be beneficial for patients with hypertension. However, this effect is usually not clinically significant enough to cause concern in most patients.

That said, there are a few considerations to keep in mind:
1. Monitoring Blood Pressure: While the combination is generally safe, it is still advisable to monitor your blood pressure regularly, especially when starting Viagra. If you experience symptoms such as dizziness, lightheadedness, or fainting, you should consult your healthcare provider.

2. Individual Health Factors: Each patient's health status is unique. Factors such as the presence of other medical conditions (e.g., heart disease, diabetes) or the use of additional medications can influence how these drugs interact. Always inform your healthcare provider about all medications you are taking and any underlying health issues.

3. Side Effects: Both medications have their own side effects. Common side effects of Cozaar include dizziness, fatigue, and potential kidney function changes, while Viagra can cause headaches, flushing, and nasal congestion. If you experience any unusual or severe side effects after taking these medications together, seek medical attention.

4. Consult Your Doctor: Before starting Viagra or any new medication, it is crucial to discuss it with your healthcare provider. They can provide personalized advice based on your medical history and current medications.

In summary, combining Cozaar with Viagra is generally considered safe, as they do not have significant interactions. However, it is essential to monitor your health and consult with your healthcare provider to ensure that this combination is appropriate for your specific situation. Always prioritize open communication with your healthcare team to manage your medications effectively and safely.

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