Can You Safely Combine Blood Pressure Medications with Viagra? - Cardiology

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Drug interactions


Currently, I am taking BLOPRESS 8mg (Candesartan) once daily and Norvasc 5mg (Amlodipine) half a tablet daily for hypertension.
Can I also take Viagra (Sildenafil)? If so, will there be any side effects? Thank you!

Jin Zai, 60~69 year old female. Ask Date: 2023/03/28

Dr. Li Han reply Cardiology


Hello, Viagra (Sildenafil) essentially has vasodilatory effects.
Caution should be exercised with many medications that have vasodilating or antihypertensive effects, especially nitrates, alpha-adrenergic blockers, alcohol, and antihypertensive drugs.
Additionally, substances that affect liver metabolism, such as grapefruit juice, should also be considered.
It may be advisable to consult a pharmacist, as they can provide you with some recommendations.
The Changhua Hospital of the Ministry of Health and Welfare cares about your well-being.

Reply Date: 2023/03/28

More Info


When considering the combination of blood pressure medications such as BLOPRESS (an angiotensin II receptor blocker) and Norvasc (a calcium channel blocker) with Viagra (sildenafil), it is essential to understand the potential interactions and side effects.
Viagra is primarily used to treat erectile dysfunction by increasing blood flow to the penis. It works by inhibiting an enzyme called phosphodiesterase type 5 (PDE5), which leads to relaxation of blood vessels and increased blood flow. While Viagra is generally safe for many individuals, there are specific considerations when it is combined with blood pressure medications.

1. Compatibility with Blood Pressure Medications: Viagra does not have a direct interaction with BLOPRESS or Norvasc. However, both BLOPRESS and Norvasc lower blood pressure, and Viagra can also cause a temporary drop in blood pressure. This can lead to additive effects, potentially causing hypotension (low blood pressure), which may result in symptoms such as dizziness, lightheadedness, or fainting, especially when standing up quickly.

2. Monitoring Blood Pressure: If you are considering taking Viagra while on BLOPRESS and Norvasc, it is crucial to monitor your blood pressure closely. If you experience any symptoms of low blood pressure, such as dizziness or fainting, you should contact your healthcare provider immediately.
3. Consulting Your Healthcare Provider: Before starting Viagra, it is advisable to consult with your healthcare provider. They can evaluate your overall health, the severity of your hypertension, and any other medications you may be taking. They may also consider your medical history, including any cardiovascular issues, to ensure that Viagra is a safe option for you.

4. Potential Side Effects: Common side effects of Viagra include headaches, flushing, nasal congestion, and upset stomach. When combined with blood pressure medications, the risk of experiencing side effects related to blood pressure changes may increase. It is essential to be aware of these potential side effects and to report any unusual symptoms to your doctor.

5. Lifestyle Considerations: In addition to medication management, lifestyle factors such as diet, exercise, and stress management play a significant role in managing blood pressure and overall cardiovascular health. Engaging in regular physical activity, maintaining a healthy weight, and following a balanced diet can help improve your blood pressure control and may enhance the effectiveness of your medications.

In summary, while it is generally safe to combine BLOPRESS and Norvasc with Viagra, careful monitoring and consultation with your healthcare provider are essential. They can provide personalized advice based on your specific health situation and help you manage any potential risks associated with this combination of medications. Always prioritize open communication with your healthcare team to ensure safe and effective treatment.

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