HSV-2: Implications of Positive IgG Test Results - Urology

Share to:

About HSV-2


Hello, doctor.
I recently underwent testing and my HSV-2 IgG level came back at 85 mIU/mL.
Does this indicate that I may have been recently infected or that I have an existing infection? I read online that a level above the normal range is considered significant, especially if it's four times higher.
However, I currently do not have any symptoms such as blisters in the genital area.
The last time I had sexual intercourse was a month and a half ago, and I used a condom.
Does this result mean that I might have a risk of developing genital herpes in the future? Is there a possibility of transmitting it to my sexual partner? Could this also affect my fertility? I saw a doctor on an online platform mention that a positive IgG result doesn't necessarily indicate an active infection, and that if we tested everyone in Taiwan, about 80% might test positive.
Should I seek any treatment? I am very worried; I initially intended to test for syphilis and HIV, but ended up with this result instead.

Niming, 30~39 year old female. Ask Date: 2018/05/14

Dr. Chen Jiansheng reply Urology


IgG typically indicates that you have had a past infection, and it does not represent an acute infection.
If there are no symptoms, treatment is not recommended.

Reply Date: 2018/05/14

More Info


Understanding the implications of a positive HSV-2 IgG test result can be quite complex and often leads to confusion and anxiety, especially when it comes to concerns about transmission, symptoms, and reproductive health.
Firstly, it's important to clarify what a positive HSV-2 IgG test result means. The IgG antibody indicates that you have been exposed to the herpes simplex virus type 2 (HSV-2) at some point in your life. This does not necessarily mean that you have an active infection or that you are currently experiencing symptoms. In fact, many individuals who test positive for HSV-2 IgG do not exhibit any symptoms at all. The presence of IgG antibodies typically suggests a past infection, and these antibodies can remain in the body for years, often for a lifetime.

Regarding your specific test result of 85 mIU/ml, this is significantly above the normal range, which can vary by laboratory but is generally considered positive if it exceeds 1.1 mIU/ml. However, the level of IgG does not correlate directly with the severity of the infection or the likelihood of transmitting the virus. It is also worth noting that many people in the general population, particularly in certain regions, may test positive for HSV-2 IgG due to past exposure. In some studies, the prevalence of HSV-2 antibodies in adults can be as high as 80%, indicating that it is a common virus.

You mentioned that you last had sexual intercourse a month and a half ago and used protection. While condoms significantly reduce the risk of transmission, they do not eliminate it entirely, especially if there are any skin-to-skin contact areas that are not covered. However, if you are not experiencing any symptoms such as sores or blisters, the likelihood of transmitting the virus is lower, but not impossible.

As for concerns about future outbreaks, it is true that once infected, there is a possibility of experiencing recurrent outbreaks, especially during times of stress, illness, or when your immune system is compromised. However, many individuals with HSV-2 lead normal lives without frequent outbreaks. The immune system often keeps the virus in check, and outbreaks can become less frequent over time.

In terms of reproductive health, having HSV-2 does not automatically mean that you cannot have children or that there will be complications during pregnancy. However, if you are pregnant or planning to become pregnant, it is crucial to discuss your HSV status with your healthcare provider. They can provide guidance on how to manage the virus during pregnancy and delivery to minimize any risks to the baby.

Regarding treatment, if you are asymptomatic and do not have recurrent outbreaks, antiviral treatment may not be necessary. Many healthcare providers recommend treatment only for those who experience frequent outbreaks or have concerns about transmission to partners. If you are feeling anxious about your diagnosis, it may be helpful to speak with a healthcare professional who can provide reassurance and discuss your options.

In summary, a positive HSV-2 IgG test indicates past exposure to the virus, but it does not mean you are currently infected or symptomatic. The majority of individuals with HSV-2 lead healthy lives, and with proper management and communication with partners, the risks of transmission can be minimized. If you have further concerns or experience any symptoms, it is advisable to consult with a healthcare provider for personalized advice and support.

Similar Q&A

Understanding HSV-2 IgG Positive Results: Implications for Marriage and Parenthood

If your HSV-2 IgG level is 71 IU/ml and the blood test is positive, it indicates that you have been infected with the herpes simplex virus type 2. This means that you can potentially transmit the virus to others, especially during an active outbreak. However, many individuals wit...


Dr. Xu Weikai reply Urology
HSV IgG in the blood persists for almost a lifetime (at least for several years) once a person has been infected. Therefore, clinically, it is only used to determine if there has been a past infection. As for whether there is active infection or infectiousness, this is generally ...

[Read More] Understanding HSV-2 IgG Positive Results: Implications for Marriage and Parenthood


Understanding HSV-2 and Eczema: Implications and Treatment Options

Hello, doctor. I recently underwent a sexually transmitted infection test and the result showed HSV-2 IgG antibodies with a value of 0.94, which is considered equivocal. Although it falls in the intermediate range, what implications might this have for the future? I also have ecz...


Dr. Chen Jiansheng reply Urology
Please seek medical attention.

[Read More] Understanding HSV-2 and Eczema: Implications and Treatment Options


Understanding Your Concerns About Genital Herpes and HSV-2 Testing

Hello Dr. Du, In 1996, I had an instance of unprotected sexual intercourse during a business trip (the only time in my life). After a certain number of days, I was tested for various sexually transmitted infections, all of which came back negative, including genital herpes (HSV ...


Dr. Du Shixi reply Urology
Hello: Herpes simplex virus can occur on any part of the body, particularly on the mouth, buttocks, genitals, and between the fingers. The most reliable way to confirm herpes simplex is through direct viral culture or antigen testing from the lesion. The positive culture rate for...

[Read More] Understanding Your Concerns About Genital Herpes and HSV-2 Testing


Understanding Weak Positive Results for Herpes Type 2 IgM Testing

Hello, doctor. I apologize for bothering you, but I would like to ask you a question. Recently, I underwent a health check-up at a laboratory, which included testing for sexually transmitted infections. The report showed: Herpes Simplex Virus Type 2 IgG: (-) 0.068, which is negat...


Dr. Du Shixi reply Urology
Hello: The test results are inconclusive, not a false positive. The results are uncertain, and you may choose to retest at a later date for comparison. Wishing you good health.

[Read More] Understanding Weak Positive Results for Herpes Type 2 IgM Testing


Related FAQ