Medication Effects on Hirsutism in PCOS Patients - Obstetrics and Gynecology

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Pharmacotherapy


Due to polycystic ovary syndrome (PCOS) causing hirsutism, I would like to ask if taking Western medication for treatment will result in the hair disappearing or if it will only slow down the growth rate?

Qq, 10~19 year old female. Ask Date: 2018/06/13

Dr. Huang Yuande reply Obstetrics and Gynecology


Polycystic ovary syndrome (PCOS) is commonly associated with symptoms such as irregular menstruation, hirsutism, and obesity.
Current pharmacological treatments include ovulation induction or hormone replacement therapy.
After medication treatment, the aforementioned symptoms can often improve significantly.
It is recommended that you seek guidance from a specialist.
Thank you for your inquiry.

Reply Date: 2018/06/13

More Info


Hirsutism, characterized by excessive hair growth in women, is a common symptom associated with polycystic ovary syndrome (PCOS). The management of hirsutism often involves pharmacological treatments that target the underlying hormonal imbalances contributing to the condition. Understanding how these medications work and their effects on hair growth is essential for patients seeking relief from this distressing symptom.

When treating hirsutism in PCOS patients, several classes of medications may be prescribed, including hormonal contraceptives, anti-androgens, and insulin-sensitizing agents. Hormonal contraceptives, such as combined oral contraceptives (COCs), can help regulate menstrual cycles and reduce androgen levels, which in turn can slow down hair growth. Anti-androgens, such as spironolactone, directly block the effects of androgens on hair follicles, leading to a reduction in hair growth over time. Insulin-sensitizing agents like metformin may also be used, particularly in patients with insulin resistance, as they can help improve metabolic parameters and potentially reduce androgen levels.

Regarding your specific question about whether the hair that has already grown will disappear or if the medication will only slow its growth, the answer is nuanced. Medications like COCs and anti-androgens can indeed slow down the growth of new hair and may also lead to a reduction in the thickness and coarseness of existing hair over time. However, it is important to note that these medications do not typically cause existing hair to fall out or disappear completely. Instead, they work to prevent further hair growth and can improve the overall appearance of hirsutism.

The timeline for seeing results can vary significantly among individuals. Some patients may notice a reduction in hair growth within a few months of starting treatment, while others may require longer periods—often six months to a year—to see significant changes. Consistency in taking the medication as prescribed is crucial for achieving the best results.

In addition to pharmacological treatments, other options such as laser hair removal or electrolysis can be considered for more immediate cosmetic relief. These methods physically remove hair and can provide longer-lasting results compared to medication alone. However, they do not address the underlying hormonal issues and may need to be combined with medication for optimal management of hirsutism in PCOS.

It's also essential to have a comprehensive approach to managing PCOS, which includes lifestyle modifications such as weight management, dietary changes, and regular exercise. These changes can help improve insulin sensitivity and hormonal balance, further aiding in the management of hirsutism.

In summary, while medications for hirsutism in PCOS can significantly slow down hair growth and improve the condition, they typically do not cause existing hair to disappear. A combination of pharmacological treatments, cosmetic procedures, and lifestyle changes can provide the most effective management strategy for hirsutism in PCOS patients. Always consult with a healthcare provider to determine the best treatment plan tailored to individual needs and circumstances.

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