Syphilis: Skin Issues and Treatment Options - Urology

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Syphilis skin issues?


Four months ago, I had sexual relations with someone.
I went for anonymous screenings twice, one month and three months (90 days) later, and both tests for HIV and syphilis came back negative.
However, I recently discovered a small bump on the inner thigh, approximately 12mm x 8mm in size, which is slightly painful when pressed, and the surface skin has peeled off.
I'm very worried that it might be syphilis.
Is syphilis treatable? Which medical specialty should I consult?

Xian Zai, 20~29 year old female. Ask Date: 2018/06/16

Dr. Sun Hongshun reply Urology


After listening to your description, if there is only a single spot, it doesn't seem very much like a rash.
However, without a photo for reference, I cannot confirm this directly.
I suggest you visit our Infectious Diseases or Urology department for a satisfactory answer.

Reply Date: 2018/06/16

More Info


Syphilis is a sexually transmitted infection caused by the bacterium Treponema pallidum. It can present with a variety of symptoms, including skin lesions, which can sometimes lead to confusion regarding diagnosis. Given your recent sexual history and the appearance of a small, painful bump on your inner thigh, it is understandable that you are concerned about the possibility of syphilis or another sexually transmitted infection (STI).

The symptoms you describe—a small bump that is tender to the touch and has peeling skin—could potentially be related to several conditions, including but not limited to syphilis. In the context of syphilis, the primary stage is characterized by the appearance of a painless sore called a chancre at the site of infection, which typically heals on its own within a few weeks. However, secondary syphilis can present with skin rashes and lesions that may be mistaken for other dermatological issues.
Given that you have tested negative for syphilis and HIV at the one-month and three-month marks, it is reassuring, but it does not completely rule out the possibility of a recent infection or other STIs. The timing of your symptoms and the nature of the bump warrant further investigation.
It is crucial to consult a healthcare provider, preferably a dermatologist or an infectious disease specialist, who can perform a thorough examination and possibly conduct additional tests. They may recommend a syphilis test again, as well as tests for other STIs, to ensure a comprehensive evaluation.
In terms of treatment, syphilis is indeed treatable, typically with antibiotics such as penicillin. The earlier the infection is diagnosed, the easier it is to treat and the less likely it is to cause long-term complications. If your bump is determined to be related to syphilis or another infection, your healthcare provider will guide you on the appropriate treatment plan.

In addition to seeking medical attention, it is essential to practice safe sex to prevent the transmission of STIs. This includes using condoms and having open discussions with partners about sexual health.
In summary, while your negative test results for syphilis and HIV are encouraging, the appearance of a new skin lesion should not be ignored. It is advisable to see a healthcare professional who can provide a proper diagnosis and treatment plan. Remember, early intervention is key in managing any potential infection effectively.

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