Probiotics and Their Role in Treating Helicobacter Pylori and Ulcers - Gastroenterology and Hepatology

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Gastric ulcers and probiotics?


Recently, a family member experienced heartburn and was diagnosed with a Helicobacter pylori infection and gastric ulcer.
It has been noted that in recent years, Bifidobacterium has shown significant progress in the prevention and treatment of food allergies, gastritis (including gastric ulcers) caused by Helicobacter pylori, and ulcerative colitis.
I would like to ask: 1.
Does Bifidobacterium truly have an effect on Helicobacter pylori infection? 2.
Are the probiotic formulations Mylisyn and Bifidobacterium longum effective in the treatment of Helicobacter pylori?

MJ, 30~39 year old female. Ask Date: 2018/06/22

Dr. Cai Anshun reply Gastroenterology and Hepatology


Hello: Traditional therapy involves the use of antibiotics for bacterial eradication.
Changhua Hospital cares about your health.
Dr.
Tsai An-shun.

Reply Date: 2018/06/22

More Info


Probiotics, particularly strains like Bifidobacterium, have garnered attention in recent years for their potential role in managing Helicobacter pylori (H. pylori) infections and related gastrointestinal conditions, such as ulcers. H. pylori is a gram-negative bacterium that colonizes the stomach lining and is a significant contributor to gastritis, peptic ulcers, and even gastric cancer. The standard treatment for H. pylori infection typically involves a combination of antibiotics and proton pump inhibitors (PPIs) to eradicate the bacteria and reduce stomach acidity, promoting healing.

1. Effectiveness of Bifidobacterium Against H. pylori: Research indicates that certain probiotic strains, including Bifidobacterium, may have a beneficial effect in the context of H. pylori infections. Probiotics can help restore the balance of gut microbiota, which may be disrupted due to antibiotic treatment. Some studies suggest that probiotics can enhance the eradication rates of H. pylori when used alongside standard antibiotic therapy. They may also help mitigate some of the side effects associated with antibiotics, such as diarrhea and gastrointestinal discomfort. However, while probiotics can be a supportive adjunct in the treatment of H. pylori, they are not a standalone treatment. The primary approach remains the use of antibiotics and PPIs.

2. Efficacy of Specific Probiotic Formulations: Regarding the specific probiotic formulations you mentioned, such as "妙利散" and "表飛鳴-樂散," the effectiveness of these products would depend on their specific strains and concentrations of probiotics. While some formulations may contain beneficial strains that could support gut health and potentially aid in the management of H. pylori, it is essential to look for clinical evidence supporting their efficacy in treating H. pylori specifically. Not all probiotics are created equal, and their effectiveness can vary widely based on the strains used and their viability.

In summary, while probiotics, including Bifidobacterium, show promise in supporting the treatment of H. pylori infections and associated conditions, they should not replace conventional antibiotic therapy. Instead, they can be considered as complementary agents that may enhance treatment outcomes and improve gastrointestinal health. It is crucial to consult with a healthcare provider before starting any probiotic regimen, especially in the context of an H. pylori infection, to ensure that it aligns with the overall treatment plan.
Additionally, if your family member is experiencing symptoms such as heartburn, it is important to address these symptoms with appropriate medical management, which may include lifestyle modifications, dietary changes, and medications as prescribed by a healthcare professional. Regular follow-ups and monitoring are essential to assess the effectiveness of the treatment and make any necessary adjustments.

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Hello: Antibiotics and proton pump inhibitors are the standard treatments. Changhua Hospital cares about your health. Dr. Tsai An-shun.

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