Breast cancer surgical pathology report inquiry?
Dear Dr.
Yuan,
My mother recently underwent a lumpectomy, and the pathology report is as follows: Distance from closest margin: IDC: < 1 mm away from 6-8 o'clock.
< 1 mm away from deep margin.
MARGIN INVOLVED BY INVASIVE CARCINOMA; Specify which margin: deep.
At first, upon seeing the pathology report, I thought it indicated that the margins were not clear, as I read online that a margin of at least 2 mm is generally required.
Additionally, the last part mentions that cancer cells are still present at the margin.
However, when I consulted with the attending physician, he assured me that the margins were clear, and that the deep margin is not a concern due to his extensive experience.
I trust his response, but I am still curious about what this means.
Thank you!
Xiao Li, 50~59 year old female. Ask Date: 2018/07/06
Dr. Yuan Tianmin reply Breast and Thyroid
Usually, this situation should be explained by your physician.
They have the best understanding of your mother's condition.
Reply Date: 2018/07/06
More Info
Understanding pathology reports following breast cancer surgery can be daunting, especially when it comes to margins and the presence of cancer cells. Your mother's report indicates that the distance from the closest margin to the invasive ductal carcinoma (IDC) is less than 1 mm, which raises concerns about whether the cancer has been completely removed. Let's break down the key components of the report and what they mean in the context of breast cancer surgery.
Key Components of the Pathology Report
1. Invasive Ductal Carcinoma (IDC): This is the most common type of breast cancer, which starts in the milk ducts and invades surrounding tissue. The report confirms the presence of IDC, which is crucial for determining the treatment plan.
2. Margins: The report states that the closest margin is less than 1 mm away from the cancerous tissue. In surgical oncology, a "margin" refers to the edge of the tissue that has been removed during surgery. A clear margin means no cancer cells are found at the edge of the removed tissue, suggesting that the cancer has been completely excised. Conversely, if cancer cells are present at the margin, it indicates that some cancer may remain in the body.
3. Distance from Margins: The report specifies that the deep margin is involved by invasive carcinoma, meaning that cancer cells are present at that margin. The standard guideline for surgical margins in breast cancer is typically 1-2 mm, depending on the type of surgery and the specific characteristics of the tumor. Margins less than 1 mm are often considered "close" and may necessitate further treatment.
Implications of the Report
Your initial concern about the adequacy of the surgery is valid, given the less than 1 mm margin. However, your surgeon's reassurance that the surgery was performed adequately is also important. Surgeons often consider various factors, including the tumor's characteristics, the patient's overall health, and the surgeon's experience. In some cases, even if the margins are close, the surgeon may feel confident that they have adequately removed the cancer, especially if they have a history of successful outcomes with similar cases.
Next Steps
1. Follow-Up Treatment: Depending on the final pathology results, including hormone receptor status and the presence of HER2, your mother's oncologist may recommend additional treatments. These could include radiation therapy, chemotherapy, or hormone therapy to reduce the risk of recurrence.
2. Monitoring: Regular follow-up appointments will be essential to monitor for any signs of recurrence. This typically includes physical exams and imaging studies as needed.
3. Communication with Healthcare Team: It's crucial to maintain open communication with your mother's healthcare team. If there are lingering concerns or questions about the pathology report or the treatment plan, do not hesitate to ask the oncologist for clarification. They can provide insights tailored to your mother's specific situation.
Conclusion
In summary, while the presence of cancer cells at the margin is concerning, it does not automatically mean that the surgery was unsuccessful. The experience and judgment of the surgeon play a significant role in determining the adequacy of the procedure. It is essential to follow up with the oncologist to discuss the next steps in treatment and monitoring. Breast cancer management is a multidisciplinary approach, and understanding the pathology report is a critical part of navigating this journey.
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