Vaginal Suppository Use and Normal Discharge - Obstetrics and Gynecology

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Issues with vaginal suppositories?


Hello Dr.
Huang, after my follow-up visit, the gynecologist mentioned that I still have a slight inflammation and prescribed oral anti-inflammatory medication and a suppository (Macmiror complex 500).
I used the suppository (one capsule) before bed last night, and this morning I noticed a yellow discharge.
I understand that this is normal, but I used the suppository around 11 PM, and even until this afternoon around 6 PM, my underwear still has a little yellow medication.
Is this also a normal situation? Thank you.

Niming, 20~29 year old female. Ask Date: 2018/07/10

Dr. Huang Jianzhong reply Obstetrics and Gynecology


After my follow-up visit, the gynecologist mentioned that I still have a slight inflammation and prescribed oral anti-inflammatory medication and a suppository (Macmiror complex 500).
I used the suppository (one) before bed last night.
This morning, I noticed yellow discharge from my vagina.
I understand that this is a normal occurrence, but I used the suppository around 11 PM last night, and even until this afternoon around 6 PM, my underwear still has some yellow medication.
Is this also a normal situation? Answer: Yes, this is also a normal situation.

Reply Date: 2018/07/10

More Info


When it comes to the use of vaginal suppositories, such as Macmiror complex, it is important to understand both the expected effects and the normal discharge that may occur following their use. Macmiror complex is an antifungal and antibacterial medication commonly prescribed for treating infections in the vaginal area. It is effective against various pathogens, including those that cause bacterial vaginosis and yeast infections.

After inserting a vaginal suppository, it is typical for some of the medication to be expelled from the vagina. This is due to the natural anatomy of the vagina, which is designed to allow for the expulsion of foreign substances. The discharge you are experiencing, particularly if it is yellow, can be a normal occurrence as the medication dissolves and is absorbed by the vaginal tissues. The duration of the discharge can vary from person to person, and it is not uncommon for some residue to remain for several hours after administration.

In your case, using the suppository around 11 PM and noticing discharge until 6 PM the next day is generally within the realm of normal. However, the characteristics of the discharge can provide additional insights. If the discharge is primarily yellow and does not have a foul odor, it is likely just the medication being expelled. If the discharge were to change in color, consistency, or odor—especially if it becomes foul-smelling or accompanied by itching, burning, or increased discomfort—it would be advisable to consult your healthcare provider. These changes could indicate a potential adverse reaction or a secondary infection.

It is also important to consider that the presence of inflammation, as noted by your gynecologist, can contribute to increased discharge. Inflammatory processes can lead to changes in the vaginal flora and may result in more noticeable discharge as the body responds to the infection.

In terms of managing your symptoms and ensuring effective treatment, here are a few recommendations:
1. Follow the Treatment Plan: Continue taking the oral anti-inflammatory medication as prescribed. Completing the full course of treatment is crucial for resolving the infection.

2. Monitor Symptoms: Keep track of any changes in your symptoms, including the nature of the discharge, any new symptoms, or worsening of existing symptoms. This information will be valuable for your healthcare provider if follow-up is necessary.

3. Hygiene Practices: Maintain good hygiene practices. Use mild, unscented soap and avoid douching or using scented products in the vaginal area, as these can disrupt the natural flora and exacerbate irritation.

4. Avoid Irritants: If you notice that certain products (like soaps, lotions, or laundry detergents) irritate your vaginal area, consider switching to hypoallergenic or fragrance-free options.

5. Consult Your Doctor: If you have any concerns about the discharge or if it persists beyond a few days, do not hesitate to reach out to your healthcare provider for further evaluation. They may want to perform additional tests to ensure that the treatment is effective and that there are no complications.

In conclusion, while the discharge you are experiencing after using the vaginal suppository is likely normal, it is essential to remain vigilant about any changes in your symptoms. Open communication with your healthcare provider will help ensure that you receive the best care possible and address any concerns you may have regarding your treatment and recovery.

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