Perimenopause Symptoms and Hormone Treatment Options - Obstetrics and Gynecology

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Premenopausal symptoms


Hello, Director: I had a blood test for menopause at the obstetrics and gynecology department, and the doctor said I have signs of perimenopause.
Due to experiencing vaginal burning, the doctor prescribed me Premarin vaginal cream and progesterone.
I would like to ask if it is safe to take progesterone during my menstrual period, or should I wait until after my period to continue using it?

Xiao Min, 40~49 year old female. Ask Date: 2018/07/23

Dr. Cao Guotao reply Obstetrics and Gynecology


Hello, the usage of progesterone can be done in a cyclical manner for the last two weeks of the menstrual cycle.
It is advisable to consult the physician who prescribed the medication for more detailed information.
Wishing you good health.

Reply Date: 2018/07/23

More Info


Perimenopause, the transitional phase leading up to menopause, can present a variety of symptoms due to fluctuating hormone levels. Common symptoms include hot flashes, night sweats, mood swings, vaginal dryness, and changes in menstrual cycles. As women approach menopause, the ovaries gradually produce less estrogen and progesterone, leading to these physical and emotional changes.

In your case, the doctor has prescribed a vaginal cream containing progesterone (普力馬林) and a medication (得胎隆) to help alleviate the burning sensation you are experiencing. Progesterone is a hormone that plays a crucial role in regulating the menstrual cycle and supporting pregnancy. It can also help counteract some of the effects of estrogen loss during perimenopause.

Regarding your question about whether you can use progesterone during your menstrual period, it is generally recommended to follow your doctor's instructions. In many cases, hormone treatments like progesterone are prescribed to be taken continuously or in a specific cycle that aligns with your menstrual cycle. If your doctor has not specified otherwise, it is typically safe to continue using the vaginal cream during your period. However, some women may experience changes in their menstrual flow or symptoms while using hormone treatments, so it is essential to monitor how your body responds.

If you have concerns about using progesterone during your menstrual period or if you experience any unusual symptoms, it is crucial to consult your healthcare provider. They can provide personalized advice based on your medical history and current symptoms.
In addition to hormone treatments, lifestyle changes can also help manage perimenopausal symptoms. Regular exercise, a balanced diet, and stress management techniques such as yoga or meditation can improve overall well-being. Some women find relief from hot flashes and mood swings through natural remedies, such as herbal supplements, but it's essential to discuss these options with your doctor to ensure they are safe and appropriate for you.

It's also worth noting that while hormone therapy can be effective in managing symptoms, it may not be suitable for everyone. Some women may have contraindications or may prefer to explore alternative treatments. Your healthcare provider can help you weigh the benefits and risks of hormone therapy and discuss other options that may be available.

In summary, you can generally continue using progesterone during your menstrual period unless advised otherwise by your doctor. It's important to maintain open communication with your healthcare provider about your symptoms and treatment options as you navigate this transitional phase. They can help you find the most effective approach to managing your perimenopausal symptoms and improving your quality of life.

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