Penile Lesions: From Moles to HPV-Related Warts - Dermatology

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The pathology report indicates that the mole on the penis is a condyloma?


Hello doctor, I have several small flat moles on my penis (the largest one measures 0.3mm x 0.3mm).
These moles have been with me for about three years.
I am concerned that they might develop into melanoma, so I consulted multiple dermatologists who all said they are benign and that there is no need for removal, advising me to monitor for any changes in elevation or size.
However, I really want them removed, so I sought help from a plastic surgeon.
The surgeon sent the excised tissue for biopsy, and the results indicated condyloma! Yet, before the biopsy, none of the doctors I consulted thought it was condyloma.
Therefore, I would like to ask:
1.
Is it possible for condyloma lesions to be visually undetectable and just happen to be located on top of the mole, meaning the mole itself is not condyloma?
2.
Could I be a carrier of condyloma without any visible lesions, but still have the pathological biopsy show features such as koilocytic changes associated with condylomata acuminata?
3.
If the pathology report indicates condyloma, does that mean I am definitely infected, or could it also indicate that I am merely a carrier of the virus, showing findings like acanthosis and koilocytic changes without active lesions?

Hua Lan, 20~29 year old female. Ask Date: 2018/08/06

Dr. Wu Yuxin reply Dermatology


1.
Possible
2.
Possible
3.
The pathology report confirms it.

Reply Date: 2018/08/06

More Info


Understanding penile lesions, particularly in the context of HPV-related warts (commonly referred to as "condyloma"), can be complex and often requires careful evaluation by healthcare professionals. Based on your description and the questions you've raised, let's delve into the nature of these lesions, their implications, and the relationship between benign moles and HPV-related conditions.

1. Can Condyloma Be Invisible to the Naked Eye?
Condyloma, or genital warts, can sometimes be subtle and may not always present as obvious lesions. They can appear flat or slightly raised and may blend in with the surrounding skin, making them difficult to identify without a thorough examination. It is possible for a condyloma to develop in the vicinity of a mole or other skin lesion, leading to confusion during visual assessments. The presence of HPV can lead to changes in the skin cells, which may not be visually apparent but can be detected histologically (through biopsy).

2. Are You a Carrier of HPV Without Visible Lesions?
Yes, it is entirely possible to be an HPV carrier without showing any visible signs or symptoms. Many individuals who are infected with HPV do not develop warts or other noticeable lesions. The virus can remain dormant in the body, and the immune system may suppress its activity. However, even in the absence of visible lesions, HPV can still be present and potentially transmissible to sexual partners. The presence of koilocytic changes (which are indicative of HPV infection) in a biopsy can suggest that the virus is active, even if no external lesions are observed.

3. Does a Pathology Report Indicating Condyloma Mean You Are Actively Infected?
A pathology report that identifies condyloma indicates that HPV-related changes have been detected in the tissue sample. This does not necessarily mean that you are experiencing an active outbreak of warts. It is possible to have HPV without visible lesions, and the report may reflect the presence of the virus in a latent form. The findings of acanthosis (thickening of the skin) and koilocytic changes are characteristic of HPV infection but do not exclusively indicate active disease.
In summary, the relationship between benign moles and HPV-related lesions can be intricate. It is crucial to follow up with your healthcare provider to discuss the implications of your biopsy results and to determine the best course of action. If you are concerned about the appearance of these lesions or the potential for malignancy, further evaluation and monitoring may be warranted.
Additionally, if you have been diagnosed with condyloma, it is essential to discuss treatment options with your healthcare provider. While some individuals may choose to have lesions removed for cosmetic reasons or to alleviate anxiety, others may opt for observation, especially if the lesions are asymptomatic and not causing distress. Regular follow-up and communication with your healthcare team are vital in managing your health and addressing any concerns you may have regarding HPV and its implications.
Lastly, consider discussing the HPV vaccine with your healthcare provider, as it can help protect against certain strains of the virus that are associated with genital warts and various cancers.

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