Can Leukemia Cells Cause Sternum Pain in Just Two Weeks? - Oncology

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Sternal tenderness


Hello, I am the person who asked question #138790.
Thank you for your response, doctor! However, I would like to ask if it is possible for leukemia cells to grow to the extent that they cause sternum tenderness and joint pain within two weeks? The report from two weeks ago was normal, but in the past few days, I have noticed tenderness in the middle of my sternum, approximately near the fourth rib (it hurts when I press it with a fingertip).
Additionally, I sometimes experience mild shooting pain on the inner and outer sides of my wrist, and the pinpoint-sized petechiae on my arms have not disappeared (I first noticed them in early July, and they have gradually increased).
Therefore, I am still feeling a bit anxious.
Currently, I do not have symptoms such as fever, headache, or dizziness.
Thank you.

C, 20~29 year old female. Ask Date: 2018/08/27

Dr. Chen Yunfang reply Oncology


I apologize for the late response: it is possible, but in reality, the likelihood is extremely low, similar to the odds of winning a major lottery; it is indeed very rare.

Reply Date: 2018/08/27

More Info


Leukemia is a type of cancer that affects the blood and bone marrow, leading to the production of abnormal white blood cells. These cells can proliferate rapidly and interfere with the normal functioning of the body. Your question about whether leukemia cells can cause sternum pain and joint pain within just two weeks is quite pertinent, especially considering the rapid nature of leukemia progression in some cases.

Firstly, it is important to understand that leukemia can lead to various symptoms, including bone pain, joint pain, and tenderness in certain areas of the body. This is primarily due to the infiltration of leukemic cells into the bone marrow and other tissues, which can cause discomfort and pain. However, the timeline for the development of these symptoms can vary significantly from patient to patient.

In your case, you mentioned that your reports were normal just two weeks ago, and now you are experiencing localized pain in the sternum area and some joint discomfort. While it is possible for leukemia to progress rapidly, it is also important to consider other potential causes for your symptoms. For instance, pain in the sternum could be related to musculoskeletal issues, such as costochondritis, which is inflammation of the cartilage connecting the ribs to the sternum. Similarly, joint pain can arise from various conditions, including arthritis or even stress-related factors.

The presence of petechiae (the small red or purple spots on the skin) that you have observed since July is also noteworthy. Petechiae can be a sign of low platelet counts, which is common in leukemia due to the crowding out of normal blood cells by leukemic cells. This symptom, combined with your current pain, warrants further investigation.

Given that you do not currently have fever, headache, or dizziness, it may suggest that you are not experiencing an acute infection, which is often associated with more severe forms of leukemia. However, the combination of your symptoms, particularly the new onset of localized pain and the history of petechiae, should prompt a thorough evaluation by a healthcare professional.

I recommend that you consult with a hematologist or an oncologist as soon as possible. They may suggest further blood tests, including a complete blood count (CBC) with differential, to assess your white blood cell count, platelet count, and hemoglobin levels. Additionally, imaging studies such as X-rays or a CT scan may be warranted to evaluate the sternum and surrounding structures for any abnormalities.

In summary, while it is possible for leukemia to cause pain in the sternum and joints, especially if there is rapid progression, it is crucial to rule out other potential causes. A timely consultation with a specialist will provide you with the necessary guidance and treatment options based on a comprehensive evaluation of your condition. Your health and peace of mind are paramount, and addressing these symptoms promptly is essential.

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