Contraceptive Effectiveness After Medication Changes - Obstetrics and Gynecology

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Contraceptive effectiveness


I was recently diagnosed with polycystic ovary syndrome.
My menstrual period started on September 8, and I began taking Dianne on September 12.
However, the medication went missing on September 20.
After seeing the doctor on September 21, I was prescribed YAZ and Provera, taking one tablet of each in the morning and two tablets of each in the evening.
Is this regimen still effective for contraception?

Niming, 20~29 year old female. Ask Date: 2018/10/01

Dr. Huang Yiwen reply Obstetrics and Gynecology


Hello, Miss Anonymous: You only missed one day of your medication, so theoretically, the chance of conception is very low, and there is still contraceptive effectiveness.

Reply Date: 2018/10/01

More Info


When it comes to understanding contraceptive effectiveness after medication changes, it is essential to consider several factors, including the type of contraceptive being used, the medications prescribed, and the timing of these medications in relation to the contraceptive regimen.

In your case, you were prescribed Dianne, which is a combined oral contraceptive pill that contains both estrogen and progestin. This type of contraceptive is generally effective in preventing ovulation and thus preventing pregnancy when taken consistently and correctly. However, you mentioned that you lost your supply of Dianne and subsequently received a prescription for Estring (likely a typo for "益斯得," which may refer to a different medication) and Provera, which is a progestin-only medication.

The key point to understand is that switching from a combined oral contraceptive (like Dianne) to a progestin-only medication (like Provera) can affect contraceptive effectiveness. Progestin-only pills (POPs) are effective in preventing pregnancy, but they require strict adherence to the dosing schedule. If you miss a dose or take it outside the recommended time frame, the effectiveness can be compromised.

In your situation, since you started taking Provera after a gap in your Dianne regimen, there are a few considerations:
1. Timing of the Switch: If you switched directly from Dianne to Provera without a gap in your contraceptive coverage, you may still have some level of protection, especially if you were taking Dianne consistently before the loss. However, if there was a significant gap (more than 24 hours without any contraceptive), the effectiveness of Provera may not be immediate.

2. Provera's Mechanism: Provera works primarily by thickening cervical mucus and thinning the uterine lining, which can prevent implantation. However, it does not consistently suppress ovulation in all women, especially if not taken at the same time every day.

3. Consulting Your Healthcare Provider: It is crucial to communicate with your healthcare provider about your specific situation. They can provide personalized advice based on your medical history, the timing of your medication changes, and any other factors that may affect your contraceptive effectiveness.

4. Backup Contraception: If there is any doubt about the effectiveness of your current contraceptive method after switching medications, it is advisable to use a backup method (such as condoms) for at least seven days after starting Provera. This precaution helps ensure that you are adequately protected against unintended pregnancy.

5. Monitoring for Side Effects: Changing contraceptive methods can also lead to side effects, including irregular bleeding or changes in menstrual patterns. It's important to monitor how your body responds to the new medication and report any concerns to your healthcare provider.

In summary, while there may still be some contraceptive effectiveness after switching from Dianne to Provera, it is essential to consider the timing of the switch, the need for strict adherence to the new medication, and the potential need for backup contraception. Always consult with your healthcare provider for tailored advice and to ensure you are adequately protected.

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