Thyroid Issues and Intrauterine Drug Delivery Systems in Women - Obstetrics and Gynecology

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Thyroid issues, intrauterine drug delivery system?


I have been diagnosed with Sjögren's syndrome and have had autoimmune thyroiditis for 3 years.
I have had two implants over a total of 6 years.
My doctor mentioned that after thyroiditis, there is a possibility of developing hypothyroidism.
Currently, my T4 and TSH levels are normal, but my thyroid antibodies are very high.
Do I need to have the implant removed?

Yuping, 40~49 year old female. Ask Date: 2018/11/09

Dr. Cai Yonglong reply Obstetrics and Gynecology


The intrauterine drug delivery system Mirena has an effective duration of 5 years.
It should be removed after six years, so please visit the obstetrics and gynecology clinic.

Reply Date: 2018/11/09

More Info


When considering the relationship between thyroid issues, particularly autoimmune thyroiditis (like Hashimoto's thyroiditis), and intrauterine drug delivery systems (IUDs), there are several important factors to take into account. Your situation involves a history of autoimmune thyroid disease, specifically dry syndrome and autoimmune thyroiditis, and the use of an IUD for contraception.

First, it's essential to understand that autoimmune thyroiditis can lead to fluctuations in thyroid hormone levels. While your current T4 and TSH levels are normal, the presence of high thyroid antibodies indicates ongoing autoimmune activity, which could potentially lead to hypothyroidism in the future. Regular monitoring of thyroid function is crucial, especially in the context of autoimmune conditions, as they can affect hormone levels and overall health.

Regarding the use of an IUD, such as the Mirena, it is generally considered safe for women with thyroid disorders. The hormonal IUD releases levonorgestrel, which primarily works locally within the uterus and has minimal systemic effects. Therefore, it is unlikely to interfere with thyroid function directly. However, individual responses can vary, and some women may experience changes in their menstrual cycle or other hormonal effects, which could be influenced by their thyroid status.

In your case, the decision to remove the IUD should be based on several considerations:
1. Thyroid Function Monitoring: Since you have a history of autoimmune thyroiditis and elevated antibodies, it is essential to continue monitoring your thyroid function regularly. If you start to experience symptoms of hypothyroidism (such as fatigue, weight gain, or changes in mood), you should consult your healthcare provider for further evaluation.

2. Symptoms and Side Effects: If you are experiencing any adverse effects from the IUD, such as heavy bleeding, pain, or other symptoms that could be related to hormonal changes, it may be worth discussing with your doctor whether removal is necessary.

3. Future Family Planning: Consider your future reproductive plans. If you are planning to conceive soon, you may want to discuss the timing of IUD removal with your healthcare provider.

4. Consultation with Specialists: Given your autoimmune condition, it may be beneficial to consult both your endocrinologist (for thyroid management) and your gynecologist (for IUD management) to ensure a coordinated approach to your health care.

5. Individual Health Factors: Each patient's situation is unique. Factors such as age, overall health, and personal preferences should also play a role in the decision-making process.

In conclusion, while having autoimmune thyroiditis does not automatically necessitate the removal of an IUD, it is crucial to maintain open communication with your healthcare providers. Regular monitoring of your thyroid function, assessing any symptoms you may experience, and considering your reproductive goals will guide you in making the best decision for your health. If you have any concerns or experience changes in your health status, do not hesitate to reach out to your healthcare provider for personalized advice.

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