Do Antibiotics Affect Birth Control Pills? Drug Interactions - Pharmacology

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Interactions of emergency contraceptive pills with other medications?


Hello, I have been taking the contraceptive pill for three months.
This month, during a seven-day break, I took medication for urinary tract infection for three days, which included dolcol, acetaminophen, and gascon.
I plan to continue taking the next pack of contraceptive pills after two days.
Will this interfere with the effectiveness of the birth control pills? I have informed my doctor that I am taking contraceptive pills.
Thank you.

Joan, 20~29 year old female. Ask Date: 2018/11/18

Dr. Chen Yuemei reply Pharmacology


Hello: Based on the information reviewed, the medication you are taking for urethritis will not affect the effectiveness of your birth control pills, regardless of whether they are taken together or not.

Reply Date: 2018/11/18

More Info


Antibiotics and their interaction with birth control pills is a common concern among women who are using hormonal contraceptives. The question of whether antibiotics can affect the efficacy of birth control pills has been a topic of discussion for many years, and it is essential to understand the nuances involved.

Generally, most antibiotics do not interfere with the effectiveness of birth control pills. The primary antibiotic that has been shown to potentially reduce the effectiveness of hormonal contraceptives is rifampin, which is used to treat tuberculosis and some other infections. Rifampin can induce liver enzymes that metabolize hormones, leading to lower levels of the contraceptive hormones in the bloodstream. However, the antibiotics commonly prescribed for urinary tract infections, such as the ones you mentioned—Dolcol (which may refer to a combination medication) and Acetaminophen (a pain reliever and fever reducer)—do not have this effect.

Acetaminophen, for instance, is not an antibiotic but a widely used analgesic and antipyretic. It does not interact with hormonal contraceptives and is considered safe to use while on birth control pills. Similarly, Dolcol, depending on its specific formulation, is unlikely to interfere with the effectiveness of your contraceptive method.

It's important to note that while most antibiotics do not affect birth control pills, there are some factors that can influence the effectiveness of hormonal contraceptives. For example, gastrointestinal issues such as vomiting or diarrhea can reduce the absorption of the pill, leading to decreased effectiveness. If you experience any gastrointestinal disturbances while taking antibiotics, it is advisable to use a backup contraceptive method, such as condoms, until you can confirm that the pill is still effective.

In your case, since you have been taking the birth control pill (悦己) for three months and have only taken antibiotics for a short duration, you should be safe. However, it is always a good practice to inform your healthcare provider about all medications you are taking, including over-the-counter drugs, to ensure that they can provide you with the best advice tailored to your specific situation.

If you have concerns about the effectiveness of your birth control method, or if you experience any unusual symptoms, it is wise to consult with your healthcare provider. They can provide reassurance and guidance based on your medical history and the specific medications you are using.

In summary, while certain antibiotics like rifampin can affect the efficacy of birth control pills, most commonly prescribed antibiotics do not. Acetaminophen and Dolcol are unlikely to interfere with your contraceptive method. Always communicate openly with your healthcare provider about your medications and any concerns you may have regarding birth control to ensure optimal reproductive health.

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