Birth Control Side Effects: From Acne to Hives - Pharmacology

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Hello, I was originally prescribed the oral contraceptive pill Qlaira by my obstetrician-gynecologist to regulate my menstrual cycle.
I have been taking it for three months, but due to numerous side effects (e.g., severe acne, nausea, water retention, and intense uterine contractions), I switched to the oral contraceptive pill Yaz on November 5th, the fifth day of my menstrual period.
The first few days of taking Yaz were normal with no side effects, but on the seventh day, I developed hives, which have persisted to this day.
I have since seen a dermatologist who mentioned that I might have a condition resembling erythema multiforme combined with urticaria.
I would like to know if this could be related to taking the contraceptive pill.
Should I discontinue the medication, or is it advisable to continue taking it for a while to see if the symptoms resolve naturally?

Mi, 20~29 year old female. Ask Date: 2018/11/27

Dr. Hou Fangmin reply Pharmacology


Hello Ms.
Mi:
Yasmin is a medication that contains 21 light yellow hormone-containing tablets, each containing 3 mg of drospirenone and 0.02 mg of ethinylestradiol.
The side effects may include erythema multiforme, breast pain, migraine, chloasma, rash, toxic skin reactions, nausea (up to 15.8%), and vomiting.
The side effects can vary from person to person, and not everyone will experience them.
You mentioned whether to discontinue the medication or continue for a while; I believe it might be safer to switch to another option or consult with your physician about whether a different medication with fewer side effects would be more suitable for you.
Wishing you peace and good health.

Reply Date: 2018/11/27

More Info


When it comes to understanding the side effects of birth control pills, it's essential to recognize that hormonal contraceptives can indeed have a variety of effects on the body, and individual responses can vary significantly. In your case, you have experienced several side effects from the oral contraceptive pill "祈麗安" (Qilian), including acne, nausea, water retention, and severe uterine contractions. After switching to "悅己" (Yueji) oral contraceptive, you initially felt fine but then developed hives and a condition resembling polymorphic erythema combined with urticaria.

Hormonal contraceptives, such as the ones you are taking, can influence skin conditions due to their effects on hormone levels. For instance, estrogen and progestin can affect sebum production and skin cell turnover, potentially leading to acne or exacerbating existing skin conditions. The nausea and water retention you experienced are also common side effects associated with hormonal contraceptives, as they can influence fluid balance and gastrointestinal function.

The development of hives (urticaria) and polymorphic erythema after starting a new medication can be concerning. While it’s not uncommon for individuals to experience allergic reactions or skin sensitivities to medications, it’s important to determine whether the birth control pill is the cause of your symptoms. In some cases, hormonal changes can lead to skin reactions, but it’s also possible that you may have developed an allergy to an ingredient in the new pill or another medication you are taking.

Given your symptoms, it is advisable to consult with your healthcare provider. They can assess whether the birth control pill is likely contributing to your skin issues and determine if you should discontinue its use. It’s crucial not to stop any medication without professional guidance, as this could lead to unintended consequences, such as an unplanned pregnancy or a return of menstrual irregularities.

In the meantime, managing your symptoms is important. If you are experiencing significant discomfort from the hives or any other skin reactions, your healthcare provider may recommend antihistamines or other treatments to alleviate your symptoms. Additionally, they may refer you to a dermatologist for further evaluation of your skin condition.

It’s also worth noting that while hormonal contraceptives can have side effects, they are generally safe and effective for most individuals. However, if you find that the side effects are intolerable or if you have concerns about their impact on your health, discussing alternative contraceptive methods with your healthcare provider is a good idea. There are many options available, including non-hormonal methods, that may better suit your needs without the adverse effects you are currently experiencing.

In summary, while it is possible that your recent skin reactions could be related to the birth control pills, it is essential to consult with your healthcare provider for a thorough evaluation and personalized advice. They can help you navigate your options and find a solution that works best for your health and well-being.

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