Persistent Urethral Swelling and Pain: Seeking Solutions for Women - Urology

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Swelling at the lower edge of the urethral opening with painful urination for one month... what should I do?


Hello, Dr.
Hsu.
I have a history of urethritis, particularly after sexual intercourse.
For general acute urinary tract infections, I have been effectively managing my condition with D-mannose, which has led to significant improvement, allowing me to avoid continuous antibiotic use (which often results in recurrent diarrhea and is truly harmful).
However, I recently encountered a situation where, despite using D-mannose, I have persistent swelling at the lower edge of the urethral opening (it looks like a little protrusion, resembling a tongue sticking out XD), and this swelling has lasted for nearly a month without improvement.
In the past, when I experienced slight pain with similar swelling at the urethral opening, urine tests typically did not detect any bacteria.
I have also consulted doctors at a teaching hospital, who provided a diagnosis of supportive care (without prescribing medication), such as increasing water intake.
I already drink at least 300-500 cc of water every hour and need to urinate every hour.
Given these factors, I would like to ask the doctor about this condition, which does not resemble typical urethritis.
How should I proceed? If the pain persists, which specialty should I consult? The last time I presented this condition to a doctor at a large hospital, the initial diagnosis was inflammation of the tissue near the urethral opening, but it was merely a speculation.
I sincerely hope to eliminate these bothersome female health issues, especially since they occur after sexual activity.

Mi Mi, 30~39 year old female. Ask Date: 2018/12/04

Dr. Xu Wencang reply Urology


Is it a urethral caruncle? There is a submucosal protrusion at the lower edge of the urethral opening.
If urinalysis is normal, topical ointment treatment may be attempted.
Further evaluation by a physician is recommended.

Reply Date: 2018/12/04

More Info


Persistent urethral swelling and pain can be quite distressing, especially when it seems to be linked to sexual activity. Given your history of recurrent urinary tract infections (UTIs) and your current symptoms, it’s essential to approach this issue with a comprehensive understanding of potential underlying causes and appropriate management strategies.

Firstly, it’s important to recognize that urethral swelling and pain can arise from various factors, including infections, inflammation, or even anatomical issues. Since you have a history of urinary tract infections, it’s possible that your symptoms could be related to chronic inflammation or irritation of the urethra, particularly if you have experienced frequent UTIs in the past.

D-mannose, which you mentioned using, is a natural sugar that can help prevent bacteria from adhering to the urinary tract lining, thus reducing the risk of infections. While it has been effective for you in managing acute infections, it may not address underlying inflammation or irritation that could be causing your persistent symptoms.
Given that you have already ruled out acute infections through urinalysis, and considering that your symptoms have persisted for about a month, it may be beneficial to explore other potential causes. Here are some considerations and recommendations:
1. Urethral Syndrome: This condition can present with symptoms similar to a UTI but without the presence of bacteria. It may be related to irritation or inflammation of the urethra. Factors such as hormonal changes, irritants (like soaps or hygiene products), or even certain foods can contribute to this syndrome.

2. Vulvodynia or Vestibulodynia: These conditions involve chronic pain in the vulvar area and can sometimes manifest as urethral discomfort. They can be exacerbated by sexual activity and may require a multidisciplinary approach for management, including pelvic floor physical therapy, topical treatments, or pain management strategies.

3. Hormonal Factors: Since you mentioned that your symptoms are more pronounced after sexual activity, hormonal changes, particularly around the time of menstruation or menopause, could be influencing your symptoms. Estrogen plays a role in maintaining the health of the vaginal and urethral tissues, and a deficiency can lead to dryness and irritation.

4. Pelvic Floor Dysfunction: Tension or dysfunction in the pelvic floor muscles can lead to pain and discomfort in the urethral area. A physical therapist specializing in pelvic health can assess and provide exercises to help alleviate this tension.

5. Consultation with Specialists: If your symptoms persist, it may be beneficial to consult with a urologist who specializes in female urology or a gynecologist with experience in vulvovaginal disorders. They can perform a thorough examination and may recommend additional tests, such as a cystoscopy, to visualize the urethra and bladder for any abnormalities.

6. Lifestyle Modifications: In addition to medical treatments, consider lifestyle changes that may help alleviate your symptoms. Staying well-hydrated, avoiding irritants (such as scented products), and practicing good hygiene can be beneficial. Additionally, pelvic floor exercises may help strengthen the muscles and reduce discomfort.

In summary, while D-mannose has been effective in managing your acute infections, it may not be sufficient for addressing the persistent urethral swelling and pain you are experiencing. A comprehensive evaluation by a specialist, along with consideration of hormonal factors, pelvic floor health, and potential underlying conditions, will be crucial in developing an effective treatment plan. Don’t hesitate to seek further medical advice to find a resolution to your symptoms.

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