Can Smegma Cause Stones or Lead to Penile Cancer? Here's What You Need to Know - Urology

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Can smegma form stones? Does it lead to penile cancer?


I have developed a ring of white material around the edge of my glans.
Initially, I thought it was pearly penile papules, but it doesn't hurt when I squeeze it, and it feels like it's not part of my body.
Some can be pulled off but bleed, while most are tightly adhered and cannot be removed.
I believe this might be hardened smegma stuck to the glans.
How can I clean it? Will using just water and body wash be effective? Could this have any long-term effects on my health, such as penile cancer? I found information suggesting that smegma might be carcinogenic.

Niming, 20~29 year old female. Ask Date: 2018/12/09

Dr. Du Shixi reply Urology


Hello: Smegma may be a carcinogen—this is possible.
Therefore, it is important to maintain cleanliness.
When removing smegma, some individuals may experience wounds, so it is essential to be cautious to avoid inflammation.
If you are unsure how to manage it, seek assistance from a physician.
Wishing you good health.

Reply Date: 2018/12/09

More Info


Smegma, a substance composed of dead skin cells, oils, and moisture, can accumulate under the foreskin in uncircumcised males. While it is a natural occurrence, poor hygiene can lead to various health issues, including infections and inflammation. In your case, the white substance you are observing around the glans (the head of the penis) may indeed be smegma that has hardened and adhered to the skin.

To address your concerns, it is essential to maintain proper hygiene. Regular cleaning of the genital area is crucial. You can clean the area with warm water and a mild soap or body wash. It is advisable to gently retract the foreskin (if you are uncircumcised) and wash the area thoroughly to remove any smegma buildup. Avoid using harsh soaps or scrubbing too vigorously, as this can irritate the sensitive skin.

Regarding your question about whether smegma can lead to penile cancer, the answer is nuanced. While smegma itself is not a direct cause of cancer, chronic irritation and inflammation of the glans and foreskin due to poor hygiene can increase the risk of developing conditions that may lead to cancer. For instance, phimosis (a condition where the foreskin cannot be retracted) and chronic inflammation can create an environment conducive to the development of cancerous changes over time. Additionally, smegma has been associated with an increased risk of infections, such as balanitis, which can also contribute to long-term complications if left untreated.

It is important to note that penile cancer is relatively rare, but certain risk factors can increase its likelihood, including:
1. Poor Hygiene: As mentioned, inadequate cleaning can lead to chronic irritation.

2. Phimosis: This condition can trap smegma and lead to inflammation.

3. Human Papillomavirus (HPV): Certain strains of HPV are linked to an increased risk of penile cancer.

4. Smoking: Tobacco use has been associated with various cancers, including penile cancer.

5. Age: The risk of penile cancer increases with age.

If you notice any persistent changes, such as unusual growths, sores that do not heal, or any other concerning symptoms, it is crucial to seek medical attention. A healthcare professional can provide a proper diagnosis and recommend appropriate treatment if necessary.

In summary, while smegma itself is not a direct cause of penile cancer, maintaining good hygiene is essential to prevent potential complications. Regular cleaning with warm water and mild soap should suffice. If you have concerns about the appearance of your genital area or if you experience any discomfort, it is advisable to consult a healthcare provider for further evaluation and guidance.

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