Interactions Between Birth Control Pills and Common Mental Health Medications - Pharmacology

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Interactions between emergency contraceptive pills and antidepressants, as well as sleeping medications?


Hello, doctor.
I have been taking antidepressants prescribed by my psychiatrist, including "Royal" Propra Tablets 10 mg (Propranolol), "Royal" Bupropion 150 mg, and Bromazepam 3 mg (Bromazin).
Recently, my gynecologist prescribed Diane-35 S.C.
tablets for 21 days for menstrual regulation and contraception.
I usually take the Bupropion before bed along with Bromazepam.
I would like to know if these medications will affect the efficacy of the oral contraceptive pill.
Thank you.

Ka Luo, 20~29 year old female. Ask Date: 2019/01/03

Dr. Liao Lingmei reply Pharmacology


Hello: There is no interaction data between Mucins and Diane-35.
However, smoking should be avoided while taking Propranolol, and alcohol consumption should be avoided while taking Bupropion, Bromazepam, and Propranolol.
Wishing you health and happiness!

Reply Date: 2019/01/03

More Info


When considering the interactions between birth control pills and common mental health medications, it is essential to understand how these medications work and their potential effects on each other. In your case, you are taking several medications, including Propranolol (a beta-blocker often used for anxiety and hypertension), Bupropion (an antidepressant), and Bromazepam (a benzodiazepine for anxiety). You have also been prescribed Diane-35, a combined oral contraceptive pill that contains estrogen and progestin.

Firstly, it is important to note that most common antidepressants, including Bupropion, do not significantly affect the efficacy of birth control pills. Bupropion is known to have a minimal impact on the metabolism of contraceptive hormones. However, there are some exceptions, particularly with certain medications that induce liver enzymes, which can potentially lower the effectiveness of hormonal contraceptives. Fortunately, Bupropion is not one of those medications.

Propranolol, while primarily used for anxiety and hypertension, does not interfere with the effectiveness of birth control pills either. It is often prescribed alongside other medications without significant interactions concerning contraceptive efficacy.

Bromazepam, as a benzodiazepine, is also not known to affect the effectiveness of birth control pills. However, it is crucial to be cautious with the combined use of benzodiazepines and other medications, as they can lead to increased sedation or other side effects.

Regarding the timing of taking these medications, it is generally advisable to follow the prescribing physician's instructions. Taking your medications at the same time each day can help maintain consistent levels in your bloodstream, which is particularly important for both mental health medications and hormonal contraceptives.

While there is no direct evidence suggesting that the combination of Diane-35 with your current medications will reduce the effectiveness of the contraceptive, individual responses can vary. It is always best to monitor how you feel and report any unusual symptoms or side effects to your healthcare provider.

Additionally, if you experience any changes in your menstrual cycle or any unexpected side effects, it is essential to consult with your healthcare provider. They can provide personalized advice based on your medical history and current medications.

In summary, the medications you are currently taking, including Bupropion, Propranolol, and Bromazepam, do not significantly interact with Diane-35 in a way that would reduce its contraceptive efficacy. However, always communicate openly with your healthcare providers about all medications you are taking, including any over-the-counter drugs or supplements, to ensure safe and effective treatment. Regular follow-ups with both your mental health and gynecological providers can help manage your overall health and address any concerns you may have regarding your medications and their interactions.

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