Long-Term Steroid Use: Risks of Cataracts and Glaucoma in Eye Care - Ophthalmology

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Use of steroids


I have had atopic dermatitis for about ten years and rely on topical corticosteroids to manage it.
I would like to ask the doctor if long-term use of corticosteroids could lead to diseases such as cataracts and glaucoma.
I am a bit concerned and unsure whether I should continue using them.
Thank you, doctor.

Mr. Lai, 20~29 year old female. Ask Date: 2019/01/05

Dr. Gao Pilin reply Ophthalmology


Hello Mr.
Lai: The likelihood of developing glaucoma or cataracts from the topical use of corticosteroid ointments is low.
If there is a need to use them, you should proceed without excessive worry, as long as you have regular check-ups with an ophthalmologist.
The ophthalmology department at Puzi Hospital in Taiwan is available on Monday, Tuesday, Thursday, and Friday mornings from 8:00 AM to 12:00 PM, and Wednesday afternoons from 1:00 PM to 4:30 PM.
Please note that online responses are for reference only; it is essential to seek care at a medical facility when necessary.
I hope to have the opportunity to serve you.
Gao Pilin

Reply Date: 2019/01/05

More Info


Long-term use of topical steroids, especially in the context of managing conditions like atopic dermatitis, raises valid concerns regarding potential side effects, particularly the risk of cataracts and glaucoma. While topical steroids are effective for controlling inflammation and providing relief from symptoms, their prolonged use can lead to systemic absorption, which may have implications for eye health.

Cataracts and Glaucoma Risks:
1. Cataracts: Corticosteroids, when used over extended periods, have been associated with the development of cataracts. This is particularly true for systemic steroids (oral or injectable), but there is also evidence suggesting that long-term use of high-potency topical steroids can contribute to cataract formation. Cataracts occur when the lens of the eye becomes cloudy, leading to blurred vision and, if untreated, can result in significant vision impairment.

2. Glaucoma: The use of steroids can increase intraocular pressure (IOP), which is a significant risk factor for glaucoma. Glaucoma is a condition that damages the optic nerve, often due to elevated IOP, and can lead to irreversible vision loss if not managed properly. The risk of developing steroid-induced glaucoma varies among individuals, with some being more susceptible than others. Regular monitoring of eye pressure is essential for anyone using steroids, particularly if used over a long duration.

Considerations for Long-Term Use:
- Monitoring: If you are using topical steroids for an extended period, it is crucial to have regular eye examinations. An ophthalmologist can monitor your intraocular pressure and assess for any signs of cataract formation.

- Alternatives: Depending on the severity of your atopic dermatitis, there may be alternative treatments available that carry a lower risk of ocular side effects. These can include non-steroidal anti-inflammatory medications, calcineurin inhibitors (like tacrolimus or pimecrolimus), or newer biologic therapies that target specific pathways in the immune response.

- Usage Guidelines: If you continue to use topical steroids, it is advisable to follow the prescribed guidelines closely. Using the lowest effective dose for the shortest duration necessary can help mitigate risks. Additionally, consider discussing with your dermatologist or healthcare provider about the possibility of tapering off or rotating with non-steroidal treatments.

- Patient Education: Being informed about the potential risks associated with long-term steroid use is essential. If you notice any changes in your vision, such as blurriness or halos around lights, or if you experience increased sensitivity to light, it is important to report these symptoms to your healthcare provider promptly.

In conclusion, while topical steroids are effective for managing atopic dermatitis, their long-term use does carry risks for cataracts and glaucoma. Regular monitoring and open communication with your healthcare providers are key to managing these risks effectively. If you have concerns about your current treatment plan, do not hesitate to discuss them with your dermatologist or an ophthalmologist to explore the best options for your situation.

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