Side effects of eye drops?
1.
If the angle is normal but there is a predisposition to "chronic" open-angle glaucoma, will long-term use of mydriatic agents induce glaucoma?
2.
I have seen different opinions online.
Doctor A says, "Long-term use should be cautious of glaucoma and retinal light damage," while Doctor B states, "There is no risk of developing glaucoma, but it may increase the risk of cataracts and macular degeneration.
The doctor pointed out that glaucoma is primarily induced by high intraocular pressure, and currently, there is no research confirming that mydriatic agents increase intraocular pressure.
Therefore, long-term use of mydriatic agents does not increase the risk of developing glaucoma.
However, mydriatic agents not only relax the ciliary muscle but also forcibly dilate the pupil.
Children who use mydriatic agents long-term may be exposed to more ultraviolet light entering the retina through the lens compared to the general population, making their eyes more sensitive to light.
Although there is currently no related research to confirm this, theoretically, if proper eye sun protection is not practiced after using mydriatic agents, it could potentially increase the risk of cataracts and macular degeneration." Which doctor's statement is correct?
3.
Is the concern about long-term use of mydriatic agents potentially inducing glaucoma referring to those with angle-closure glaucoma? If a patient has open-angle glaucoma, can they be reassured that long-term use of mydriatic agents does not pose a risk of inducing glaucoma?
Daniel, 20~29 year old female. Ask Date: 2020/11/17
Dr. Gao Pilin reply Ophthalmology
Hello Daniel: Open-angle glaucoma is less likely to experience acute attacks due to mydriatic agents.
Closed-angle glaucoma is more prone to such occurrences.
Mydriatic agents cause the pupils to dilate, increasing the amount of light entering the eye.
Prolonged exposure to bright light can lead to a higher risk of cataracts and retinal damage, so special attention is required.
In Taiwan, the ophthalmology department at Puzi Hospital is open on Mondays, Tuesdays, Thursdays, and Fridays from 8:00 AM to 12:00 PM, and on Wednesdays from 2:00 PM to 4:30 PM.
Online responses should only be used as a reference; if necessary, it is important to seek medical attention at a healthcare facility.
I hope to have the opportunity to serve you.
Gao Pilin
Reply Date: 2020/11/17
More Info
The use of mydriatics (dilating eye drops) over an extended period raises important questions regarding their safety and potential risks, particularly concerning glaucoma and other eye conditions. Let's address your questions systematically.
1. Long-term Use of Mydriatics and Open-Angle Glaucoma: If you have normal angles but are predisposed to chronic open-angle glaucoma, the long-term use of mydriatics may not directly induce glaucoma. However, it is essential to monitor your eye pressure regularly. Mydriatics can cause temporary increases in intraocular pressure (IOP) in some individuals, particularly those with pre-existing conditions. Regular check-ups with your eye care provider are crucial to ensure that your eye pressure remains within a safe range.
2. Conflicting Opinions Among Physicians: The statements from the two doctors reflect a nuanced understanding of the risks associated with long-term mydriatic use. Doctor A's caution about the potential for glaucoma and retinal damage is valid, especially considering that prolonged dilation can lead to increased exposure to UV light, which may contribute to cataracts and macular degeneration over time. On the other hand, Doctor B's assertion that there is no evidence linking mydriatics to increased glaucoma risk is also supported by current research, which indicates that mydriatics do not significantly elevate IOP in individuals without angle closure. However, the concern about increased UV exposure and its implications for cataracts and macular degeneration is a legitimate consideration. Therefore, both perspectives hold merit, and the best approach is to balance the benefits of mydriatic use with appropriate protective measures, such as wearing UV-blocking sunglasses.
3. Risk of Glaucoma in Open-Angle vs. Angle-Closure Patients: The concern about mydriatics potentially inducing glaucoma primarily pertains to individuals with angle-closure glaucoma, where the dilation of the pupil can lead to a blockage of the drainage angle, causing a rapid increase in IOP. In contrast, individuals with open-angle glaucoma typically do not face the same risk from mydriatics, as their drainage angle remains open. However, it is still essential for anyone with a history of glaucoma or elevated IOP to use mydriatics under the supervision of an eye care professional. Regular monitoring of eye pressure and visual field tests can help mitigate any risks associated with their use.
In summary, while long-term use of mydriatics in individuals with normal angles may not inherently increase the risk of glaucoma, it is crucial to remain vigilant about eye health. Regular check-ups, monitoring of intraocular pressure, and protective measures against UV exposure are essential components of a comprehensive eye care strategy. If you have concerns about your specific situation, discussing them with your eye care provider is the best course of action. They can provide personalized advice based on your medical history and current eye health status.
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