Muscle Relaxants: Are They Causing Joint Noises? - Orthopedics

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Muscle relaxants and joint relaxants?


Hello Dr.
Li: I have been experiencing shoulder and neck pain, and my doctor prescribed me Tizanidine 2mg tablets as a muscle relaxant.
I have been taking one tablet each night for a week.
On the seventh day after taking the medication, I noticed that my joints make sounds when I move, and I also hear them when I turn over while lying flat.
Could this be related to the muscle relaxant? Will it get better? Thank you!

YOYO, 40~49 year old female. Ask Date: 2019/01/14

Dr. Li Yongheng reply Orthopedics


Hello, this situation should not be related to skeletal muscle relaxants.
It is normal for joints to make sounds during movement; it is advisable to engage in more joint activities to increase flexibility and reduce joint stiffness.

Reply Date: 2019/01/14

More Info


Muscle relaxants, such as Tizanidine, are commonly prescribed to alleviate muscle spasms and discomfort associated with conditions like neck and shoulder pain. While these medications can be effective in reducing muscle tension, they may also lead to some unexpected side effects, including the phenomenon of joint noises during movement.

When you take a muscle relaxant, it works by inhibiting nerve signals that cause muscle contractions. This can lead to a reduction in muscle tightness and spasms, which is beneficial for relieving pain. However, as the muscles relax, the dynamics of how your joints move may change. The sounds you are experiencing, often described as popping, cracking, or clicking, can occur due to several reasons:
1. Changes in Joint Mechanics: As muscles relax, they may no longer provide the same level of support or stabilization to the joints. This can lead to altered movement patterns, which may cause the ligaments and tendons to shift over the joint surfaces, resulting in audible sounds.

2. Gas Bubbles: Joints contain synovial fluid, which lubricates them and allows for smooth movement. Sometimes, gas bubbles form in this fluid and can burst when the joint is moved, creating a popping sound. This is a common occurrence and is usually harmless.

3. Tendon Movement: As muscles relax, tendons may move more freely over the bony structures of the joint. This movement can create sounds as the tendon snaps back into place after being displaced during motion.

4. Increased Awareness: When you are experiencing discomfort or pain, you may be less aware of the sounds your body makes. Once the pain subsides due to muscle relaxants, you may become more attuned to these noises, which may have been present before but unnoticed.

Regarding whether these sounds are a cause for concern, it is generally not alarming if there is no accompanying pain or discomfort. However, if the noises are accompanied by pain, swelling, or a decrease in joint function, it would be advisable to consult with your healthcare provider. They may recommend further evaluation to rule out any underlying joint issues or injuries.

As for whether the sounds will resolve, it often depends on the individual and the underlying cause of the noises. If the muscle relaxants effectively alleviate the muscle tension and pain, your body may gradually adjust to the changes, and the sounds may diminish over time. However, if the noises persist or worsen, it would be prudent to discuss this with your doctor, who may consider adjusting your treatment plan or conducting further assessments.

In summary, while muscle relaxants like Tizanidine can lead to changes in how your joints function and may result in audible sounds during movement, these noises are typically not a cause for concern if they are not associated with pain. Monitoring your symptoms and maintaining open communication with your healthcare provider will help ensure that any potential issues are addressed promptly.

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