Medication Side Effects: Hunger and Psychiatric Drugs - Psychiatry

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Medication consultation


Hello Doctor: The doctor I consulted previously prescribed me the following medications: JEXIT S.C.
Tablets 0.5 mg and U-chi Aprazo 0.5 mg.
Last week, I mentioned to the doctor that I was still having trouble sleeping, so the medication was adjusted to: JEXIT S.C.
Tablets 0.5 mg and KINAX Tablets 1 mg (Alprazolam).
After taking the medication, I noticed that I get hungry easily.
I found through online research that psychiatric medications can also cause increased appetite.
I had my blood sugar checked in December, and my hemoglobin A1c was 5.5, which is within the normal range.
Could this be caused by the medication?

Niming, 20~29 year old female. Ask Date: 2019/01/15

Dr. Huang Xiaoxian reply Psychiatry


DEAR Leo: Thank you for your question! The medication your doctor adjusted, KINAX Tab.
1mg "kingdom Alprazolam," differs from the original U-chi Aprazo 0.5mg only in dosage, which has been doubled; however, it remains within a reasonable dosage range and is essentially the same medication.
Its primary function is to provide sedation with sleep-inducing effects.
While some psychiatric medications can indeed increase appetite, the likelihood of Alprazolam causing increased appetite is low.
It is advisable to discuss other potential options for appetite enhancement with your treating physician.
On the other hand, your hemoglobin A1c levels are within the normal range, and maintaining an exercise routine is generally considered beneficial for diabetes prevention.
Wishing you all the best.

Reply Date: 2019/01/15

More Info


The experience of increased hunger while taking psychiatric medications, such as JEXIT (which contains a benzodiazepine) and KINAX (Alprazolam), is not uncommon. Many psychiatric medications can influence appetite and weight, either by increasing hunger or altering metabolism. In your case, it seems that the adjustment in your medication regimen has led to this side effect.

Benzodiazepines, like Alprazolam, are primarily used to treat anxiety and insomnia. While they are effective for these conditions, they can also have side effects that vary from person to person. Increased appetite or cravings for food can occur as a side effect of these medications. This may be due to several factors, including changes in brain chemistry, alterations in metabolism, or even behavioral changes related to the medication's sedative effects.

In addition to benzodiazepines, other classes of psychiatric medications, such as certain antidepressants (especially SSRIs and SNRIs), antipsychotics, and mood stabilizers, are known to cause weight gain and increased appetite. For instance, medications like Olanzapine and Quetiapine are notorious for causing significant weight gain in some patients. Although Alprazolam is not typically associated with weight gain to the same extent, individual reactions can vary widely.

It's good to hear that your blood sugar levels are within the normal range, as this is an important factor to monitor, especially if you are experiencing changes in appetite and weight. Maintaining a healthy diet and regular physical activity can help mitigate some of the weight gain associated with these medications.

If you find that the increased hunger is bothersome or leading to unwanted weight gain, it is essential to discuss this with your healthcare provider. They may consider adjusting your medication or dosage, or they might suggest strategies to manage your appetite. It’s crucial not to stop or adjust your medication without consulting your doctor, as this could lead to withdrawal symptoms or a resurgence of anxiety or insomnia.

In summary, while it is possible that the medications you are taking are contributing to your increased hunger, individual responses can vary. It is essential to maintain open communication with your healthcare provider about any side effects you experience, as they can help you find the best approach to manage your symptoms while minimizing unwanted side effects.

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