Progesterone: Effects on Menstruation and Urinary Changes

Progestin

I would like to ask Dr.
Huang some questions.
I have been experiencing abdominal pain, lower back pain, and a delay in my menstrual period.
Therefore, I visited a clinic where the doctor performed a urine test and an abdominal ultrasound, both of which indicated that I am not pregnant.
The internal examination did not reveal anything significant; the doctor only mentioned inflammation and prescribed antibiotics.
However, the inflammation has not improved for over a month.
The doctor then prescribed a medication to induce menstruation (Nordron) for three days, with a dosage of three pills per day.
After taking the last dose yesterday morning, I noticed a sudden increase in vaginal discharge, which is thick and white.
Today, I am experiencing frequent urination, with an increased number of trips to the bathroom, but the volume is the same as usual, and there is no pain during urination or any bleeding.
I would like to ask:
Q1: Can inflammation of the uterus or ovaries cause a missed period?
Q2: After taking the medication to induce menstruation, could the decrease in progesterone lead to frequent urination?
Q3: Is it normal to have such discharge after taking the medication to induce menstruation?
Thank you for your assistance, Dr.
Huang.

Xiao Lin, 10~19 year old female. Ask Date: 2019/01/16

Dr. Huang Jianzhong reply Obstetrics and Gynecology

Due to abdominal pain, lower back pain, and a delayed menstrual period, I visited a clinic where the doctor performed a urine test and an abdominal ultrasound, both indicating no pregnancy.
The internal examination did not reveal anything significant; the doctor only mentioned inflammation and prescribed antibiotics.
However, the inflammation has not improved for over a month.
The doctor then prescribed a medication to induce menstruation (Nordron) for three days, with a dosage of three tablets per day.
After taking the last dose yesterday morning, I suddenly noticed an increase in vaginal discharge, which is thick and white.
Today, I am experiencing frequent urination, with an increased number of trips to the bathroom, but the volume is normal, and there is no pain during urination or any bleeding.

I would like to ask:
Q1: Can inflammation of the uterus or ovaries cause a missed period?
A: Inflammation of the uterus or ovaries does not cause a missed period.
Q2: After taking the medication to induce menstruation, could a decrease in progesterone cause frequent urination?
A: A decrease in progesterone does not cause frequent urination.
Q3: Is it normal to experience that kind of discharge after taking the medication to induce menstruation?
A: Yes, it is normal.

Reply Date: 2019/01/16

More Info

Understanding the effects of medications like progesterone on menstruation and urinary changes is crucial for managing reproductive health. Based on the information provided, let's address your questions systematically.

Q1: Can inflammation of the uterus or ovaries cause a delay in menstruation?
Yes, inflammation of the uterus (endometritis) or ovaries (oophoritis) can indeed lead to menstrual irregularities, including delayed or missed periods. Inflammation can disrupt the normal hormonal signaling required for ovulation and menstruation. When the body is under stress from an infection or inflammation, it may prioritize healing over reproductive functions, which can result in a delay in menstruation. Additionally, the hormonal balance may be affected, leading to changes in the menstrual cycle.

Q2: Does taking a medication like Nordron (which contains progesterone) lead to urinary frequency due to a decrease in progesterone levels?
Nordron is typically used to induce menstruation by providing a dose of synthetic progesterone. After completing the course of such medication, the body may experience a drop in progesterone levels, which can lead to various physiological changes. However, increased urinary frequency is not a common direct side effect of decreased progesterone. Instead, it could be related to other factors, such as the body's response to the hormonal changes or the underlying inflammation. If the urinary frequency persists or is accompanied by discomfort, it is advisable to consult a healthcare provider for further evaluation.

Q3: Is it normal to experience increased white discharge after taking a medication like Nordron?
The increase in white discharge you are experiencing after taking Nordron can be attributed to several factors. Hormonal medications can alter the vaginal environment and cervical mucus production. Progesterone can lead to thicker cervical mucus, which may appear as increased white discharge. This is generally considered normal, especially if the discharge is not accompanied by an unpleasant odor or irritation. However, if the discharge changes in color, consistency, or odor, or if you experience any discomfort, it is essential to seek medical advice.

Additional Considerations
1. Monitoring Symptoms: It is important to monitor your symptoms closely. If you notice any significant changes in your menstrual cycle, urinary habits, or discharge, it is advisable to follow up with your healthcare provider.

2. Potential Side Effects of Medications: Medications like Nordron can have side effects, including mood changes, breast tenderness, and alterations in menstrual flow. If you have concerns about side effects, discussing them with your doctor can help you weigh the benefits and risks of continuing the medication.

3. Underlying Conditions: If inflammation persists or if there are recurrent issues with your menstrual cycle, further investigation may be warranted. Conditions such as polycystic ovary syndrome (PCOS), endometriosis, or pelvic inflammatory disease (PID) could contribute to these symptoms.

4. Hydration and Diet: Maintaining proper hydration and a balanced diet can also influence urinary frequency and overall reproductive health. Sometimes, dietary changes or increased fluid intake can lead to more frequent urination.

In conclusion, while hormonal medications can lead to changes in menstruation and urinary patterns, it is essential to consider the broader context of your health. If you have ongoing concerns or if your symptoms worsen, please consult your healthcare provider for a thorough evaluation and personalized advice.

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