Does Long-Term Medication Affect Future Pregnancy Chances? - Pharmacology

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Does medication affect future pregnancies?


Hello doctor, I have been diagnosed with ankylosing spondylitis and I am currently taking Baolingmei Bone Health Tablets 15mg (one tablet after dinner).
I would like to inquire whether this medication will affect my future pregnancy, as I plan to get married and have children in about three years.
I am concerned that this medication may lead to infertility, and I would like to know if I need to stop taking it for a certain period before trying to conceive.

Yi, 20~29 year old female. Ask Date: 2019/02/26

Dr. Chen Yuemei reply Pharmacology


Hello: Baoling Meigujian tablets (ingredient: meloxicam) belong to the class of non-steroidal anti-inflammatory drugs (NSAIDs) and are used for pain relief.
They do not affect future pregnancies, and literature indicates that this medication should only be avoided after 30 weeks of pregnancy.
Therefore, you can rest assured.

Reply Date: 2019/02/26

More Info


Long-term medication can indeed have implications for future pregnancy chances, and it's important to consider both the specific medication and the underlying health condition being treated. In your case, you mentioned that you are taking a medication called "寶齡美骨健錠" (likely a supplement or medication for bone health) for ankylosing spondylitis. While I cannot provide specific information about this medication without knowing its active ingredients, I can offer some general insights into how long-term medication use may affect fertility and pregnancy.

Firstly, it's essential to understand that certain medications can impact fertility in both men and women. For women, medications that affect hormone levels, such as some antidepressants, antipsychotics, and certain anti-inflammatory drugs, can potentially disrupt the menstrual cycle or ovulation, thereby affecting fertility. In men, medications that alter testosterone levels or sperm production can lead to reduced sperm counts or motility.

In the case of medications that are primarily used to manage chronic conditions, such as ankylosing spondylitis, the impact on fertility may be less direct. However, some medications used to treat autoimmune conditions can have implications for pregnancy. For instance, non-steroidal anti-inflammatory drugs (NSAIDs) and certain immunosuppressants can affect ovulation and may not be recommended during pregnancy due to potential risks to fetal development.

Regarding your specific medication, if it is a supplement aimed at improving bone health, it is less likely to have a direct impact on fertility. However, it's crucial to consult with your healthcare provider about the specific ingredients and their potential effects on pregnancy. They can provide tailored advice based on your health history and the medication's profile.

If you are planning to conceive in the next few years, it is advisable to have an open discussion with your doctor about your long-term medication use. They may suggest a plan for gradually tapering off certain medications or switching to alternatives that are safer for pregnancy. Generally, it is recommended to stop or switch medications at least three months before trying to conceive, but this can vary based on the specific medication and your health needs.

Additionally, maintaining a healthy lifestyle can support your fertility. This includes a balanced diet, regular exercise, managing stress, and avoiding smoking and excessive alcohol consumption. These factors can all contribute to better reproductive health and improve your chances of a successful pregnancy.

In summary, while long-term medication can potentially affect future pregnancy chances, the specific impact depends on the medication and the underlying health condition. It is essential to consult with your healthcare provider to assess your situation and create a plan that supports your reproductive goals while managing your health condition effectively. They can provide the most accurate information and guidance tailored to your needs.

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