Long-Term Use of Diane 35: Effects on Future Pregnancy and Cold Medication - Obstetrics and Gynecology

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Birth control pills


I have already had one child, and I would like to ask if taking Diane 35 contraceptive pills for a long period of 1-2 years will affect my future ability to conceive.
If I catch a cold and need to take cold medicine, can I continue taking Diane 35? Thank you.

Xun, 20~29 year old female. Ask Date: 2006/03/02

Dr. Li Guanghan reply Obstetrics and Gynecology


Hello: 1.
There are many types of contraceptive pills; if you are simply looking for contraception and do not have issues with elevated androgen levels (such as acne), a standard contraceptive pill will suffice.
2.
Generally, contraceptive pills do not affect future fertility, but it is important to note that fertility naturally declines with age.
3.
If you would like to inquire about drug interactions, please provide the English generic names for the medications so that I can look them up.
Hsinchu City Hospital, Department of Obstetrics and Gynecology.

Reply Date: 2006/03/02

More Info


Diane 35 is a combined oral contraceptive pill that contains cyproterone acetate and ethinyl estradiol. It is primarily used for contraception and also for treating conditions like acne and hirsutism due to its anti-androgenic properties. Your concerns about long-term use and its effects on future pregnancies, as well as interactions with cold medications, are valid and important to address.


Long-Term Use of Diane 35 and Future Pregnancy
1. Impact on Fertility: Long-term use of Diane 35, or any combined oral contraceptive, does not have a lasting negative impact on fertility. Studies have shown that fertility typically returns to baseline levels shortly after discontinuation of the pill. However, it is important to note that fertility naturally declines with age, particularly after 35 years. Therefore, while Diane 35 itself does not affect your ability to conceive in the long term, your age may play a more significant role in your fertility.

2. Duration of Use: Using Diane 35 for 1-2 years is generally considered safe for most women. However, it is advisable to have regular check-ups with your healthcare provider to monitor any potential side effects, such as changes in blood pressure, weight, or mood. If you experience any adverse effects, your doctor may suggest alternative contraceptive methods or a different formulation.

3. Breaks from the Pill: Some healthcare providers recommend taking breaks from hormonal contraceptives to allow the body to reset. However, this is not universally required. If you are not experiencing any side effects and are satisfied with the contraceptive's effectiveness, you may not need to take a break. Discussing this with your healthcare provider can help you make an informed decision based on your health history and personal circumstances.


Cold Medications and Diane 35
When it comes to taking cold medications while on Diane 35, most over-the-counter cold medications do not interact negatively with oral contraceptives. However, it is essential to be cautious with certain medications:
1. Antibiotics: While most antibiotics do not affect the efficacy of combined oral contraceptives, some, like rifampicin, can reduce their effectiveness. Doxycycline, which you mentioned in a previous question, is generally not known to interfere with the effectiveness of Diane 35, but it is always best to consult with your healthcare provider or pharmacist regarding specific medications.

2. Other Cold Medications: Common cold medications, including decongestants and antihistamines, typically do not affect the efficacy of Diane 35. However, always check the active ingredients and consult with a healthcare professional if you are unsure.


Conclusion
In summary, long-term use of Diane 35 is generally safe and should not adversely affect your future fertility. If you are considering pregnancy after stopping the pill, it is advisable to wait for at least one normal menstrual cycle to ensure your body has returned to its natural rhythm. Regarding cold medications, most can be taken safely alongside Diane 35, but always verify with a healthcare provider to avoid any potential interactions. Regular consultations with your healthcare provider will help ensure that your contraceptive method remains suitable for your health needs and lifestyle.

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