Abnormal Menstrual Issues: Why Diane 35 Was Prescribed - Pharmacology

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Menstrual irregularities?


I have irregular menstruation due to obesity.
When I first went to see a doctor, an ultrasound showed that my uterus is slightly atrophied.
The doctor ordered a blood test, and the results indicated that my androgen levels are elevated.
Additionally, my uterus or something inside it appears similar to that of a menopausal woman.
As a result, the doctor prescribed Diane 35 for me to take continuously for one month, one pill daily.
However, I checked the drug dictionary, and it is indicated for acne, hirsutism, and contraception, and it can cause side effects such as headaches and stomach pain.
Why would the doctor prescribe this medication? Please help me understand.
Thank you.
PS: I have not engaged in sexual intercourse yet.

eleven, 20~29 year old female. Ask Date: 2004/10/10

Dr. Lin Zhenjun reply Pharmacology


Hello! The components of Diane 35 are 2 mg of cyproterone acetate (an anti-androgen) and 0.035 mg of ethinyl estradiol (a synthetic estrogen).
According to the text, [blood tests showed elevated androgen levels], which is why the physician prescribed this medication.
The side effects mentioned are part of Diane 35.
Users are reminded that if they experience any discomfort after taking the medication, they should consider whether it may be drug-related.
It is advisable to return to the hospital for evaluation and discuss with a physician or pharmacist.
The side effects of medications can vary based on individual constitution and severity of symptoms.
Recommendation: If you are unwell, please consult a qualified physician for a thorough examination.
Communicate any concerns with your doctor.
Wishing you health and happiness!

Reply Date: 2004/10/10

More Info


Diane 35, which contains cyproterone acetate and ethinylestradiol, is primarily known for its use in treating conditions like acne, hirsutism (excessive hair growth), and as a contraceptive. However, it is also prescribed for managing hormonal imbalances that can lead to menstrual irregularities, particularly in women with conditions such as polycystic ovary syndrome (PCOS) or elevated androgen levels.

In your case, the prescription of Diane 35 seems to be a strategic approach to address your abnormal menstrual issues stemming from obesity and elevated male hormone levels (androgens). The ultrasound findings indicating uterine atrophy and the hormonal imbalance suggest that your body may not be responding normally to estrogen, which can lead to irregular menstrual cycles. The goal of prescribing Diane 35 is to help regulate your menstrual cycle by providing a stable dose of hormones that can counteract the effects of excess androgens.

The components of Diane 35 work in several ways:
1. Hormonal Regulation: Cyproterone acetate acts as an anti-androgen, which means it can help reduce the effects of male hormones that may be causing symptoms like irregular periods or excessive hair growth. Ethinylestradiol, an estrogen, helps stabilize the endometrial lining and promotes regular shedding during menstruation.

2. Menstrual Cycle Normalization: By providing a consistent hormonal environment, Diane 35 can help restore a more regular menstrual cycle, which is particularly important for women experiencing irregularities due to hormonal imbalances.

3. Weight Management: While Diane 35 is not a weight loss medication, managing hormonal levels can sometimes aid in weight management, as hormonal imbalances can contribute to weight gain or difficulty losing weight.

Regarding the side effects you mentioned, such as headaches and gastrointestinal discomfort, these are indeed potential side effects of Diane 35, as with many hormonal medications. It is essential to monitor how your body responds to the medication and communicate any adverse effects to your healthcare provider. They may adjust the dosage or suggest alternative treatments if the side effects become problematic.

It's also important to note that while Diane 35 can be effective in managing symptoms, it does not address the underlying causes of obesity or hormonal imbalance. Therefore, it would be beneficial to combine this treatment with lifestyle modifications, such as a balanced diet and regular exercise, to achieve better overall health and potentially improve your menstrual health.

In summary, your doctor likely prescribed Diane 35 to help regulate your menstrual cycle and manage the effects of elevated androgen levels. It's a common approach for women with similar hormonal issues, and while it has its potential side effects, the benefits in terms of menstrual regulation and hormonal balance can be significant. Always keep an open line of communication with your healthcare provider regarding your treatment and any concerns you may have.

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