Radiopharmaceuticals and Pregnancy: Safety Concerns for Healthcare Workers - Radiology

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Radiopharmaceuticals and Pregnancy


Hello, Director Wang.
I am a newcomer about to enter this field and am preparing for pregnancy.
However, my job requires me to administer medications containing radioactive elements to patients.
Since patients release radiation after receiving these medications, I will be wearing a lead apron for protection while working.
I am concerned about the following issues:
1.
How effective is the protection provided by the lead apron? Can it completely protect the eggs or the fetus?
2.
Are there any risks to other unprotected areas of my body (upper body)?
3.
Does radiation remain in the body? Could it affect my family (since I have children and elderly at home)? If there is residual radiation, what methods can be used to eliminate it?

Miss Wu, 40~49 year old female. Ask Date: 2019/04/19

Dr. Wang Yifen reply Radiology


Hello, radiation exposure can be categorized into two types: external exposure and internal exposure.
External exposure refers to the exposure of the body to ionizing radiation from outside sources.
To reduce the radiation dose from external exposure, one can shorten the exposure time (Time), choose appropriate shielding materials to block radiation (Shielding), and maintain a safe distance from the radiation source (Distance).
Internal exposure occurs when radioactive substances are deposited within the body.
The primary routes for radioactive material to enter the body include ingestion (contaminated food or water) and inhalation (breathing in gases, dust, or smoke containing radioactive materials), while secondary routes include skin or wound contact with radioactive substances.
Proper use of lead aprons can reduce the radiation dose from external exposure and help prevent radiation harm.
For areas of the body not covered by lead aprons (such as the upper body), whether facing an X-ray machine or radioactive materials, it is advisable to apply the TSD principle (Time, Shielding, Distance) interactively to avoid radiation harm.
According to the International Commission on Radiological Protection (ICRP) report 103, doses below 100 millisieverts (including single or multiple exposures) do not cause clinical functional impairment.
External radiation exposure does not remain in the body, thus it does not pose a risk to family members.
However, internal radiation exposure may affect surrounding individuals.
Once the radiation source is expelled from the body or the radiation energy decays to background levels, there will be no further impact.
The method for expelling internal radiation depends on the cause.
Since you mentioned that your work involves administering medications containing radioactive elements to patients, it is crucial to adhere to operational protocols and safety precautions, such as avoiding eating and drinking, and not to take this lightly.
Additionally, discuss your work responsibilities with your supervisor to implement appropriate radiation protection measures to prevent harm to the fetus.
Wishing you safety and health.

Reply Date: 2019/04/19

More Info


When it comes to the safety of healthcare workers handling radiopharmaceuticals, especially those who are pregnant or planning to become pregnant, there are several important considerations to keep in mind. The concerns you raised are valid and reflect a responsible approach to both personal and patient safety.

1. Effectiveness of Lead Aprons: Lead aprons are designed to reduce exposure to ionizing radiation. They are effective in shielding the body from scattered radiation, particularly during procedures involving X-rays or radiopharmaceuticals. However, while lead aprons can significantly reduce radiation exposure to the abdomen, they do not provide complete protection for the ovaries or fetus. The effectiveness of lead aprons depends on their thickness and the energy of the radiation. For instance, a standard lead apron can attenuate most of the radiation, but it is crucial to remember that no protective measure can guarantee 100% safety. Therefore, minimizing exposure time and maintaining a safe distance from the radiation source are also essential strategies.

2. Exposure of Unprotected Areas: Areas of the body not covered by lead aprons, such as the upper body, can still be exposed to radiation. The principle of Time, Distance, and Shielding (TDS) should be applied. This means that reducing the time spent near the radiation source, increasing the distance from it, and using appropriate shielding can help minimize exposure. It is advisable to follow institutional protocols for radiation safety, which often include guidelines for positioning and protective measures during procedures.

3. Radiation Residuals in the Body: Radiation exposure from external sources does not result in residual radiation within the body. However, if a healthcare worker were to ingest or inhale radioactive materials, that could lead to internal contamination. In the case of handling radiopharmaceuticals, the primary concern is ensuring that no contamination occurs through improper handling or exposure. If a patient receives a radiopharmaceutical, they may emit radiation for a period, but this does not mean that the healthcare worker will retain any radiation. It is important to follow safety protocols to prevent contamination and to ensure that any potential exposure is minimized.

4. Impact on Family Members: The concern about radiation exposure affecting family members, particularly children and the elderly, is understandable. However, as long as proper safety measures are followed, and the healthcare worker does not carry any radioactive materials home (which should not happen with proper protocols), there should be no risk of radiation exposure to family members. After a patient receives a radiopharmaceutical, they may need to follow specific guidelines regarding contact with others, especially vulnerable populations, but this is primarily a concern for the patient rather than the healthcare worker.

5. Elimination of Radiation: If there were any internal contamination (which is unlikely with proper handling), the body has natural processes for eliminating radioactive materials, often through urine or feces. Hydration and maintaining a healthy diet can support these processes. However, it is crucial to avoid any situations that could lead to internal contamination in the first place.

In conclusion, while working with radiopharmaceuticals does pose some risks, adhering to established safety protocols, using protective equipment like lead aprons, and following the TDS principles can significantly mitigate these risks. If you are planning to become pregnant, it is advisable to discuss your concerns with your supervisor or a radiation safety officer at your workplace. They can provide specific guidance tailored to your work environment and help ensure that both your health and the health of your future child are protected. Always prioritize communication and education regarding radiation safety in your workplace.

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