Can You Still Use Unsealed 75% Alcohol? Shelf Life and Safety Tips - Pharmacology

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Issues with the preservation of medicinal alcohol?


Hello, I just found a bottle of 75% alcohol that wasn't tightly sealed in the cabinet.
I would like to ask: 1.
Can the alcohol that wasn't sealed still be used, or could bacteria have entered it? 2.
How long can alcohol be used after opening? Thank you.

KENE, 20~29 year old female. Ask Date: 2019/04/24

Dr. Liao Huiling reply Pharmacology


1.
Alcohol is classified as a volatile substance, and not securely closing the cap after opening can affect its efficacy.
However, under normal circumstances, 75% alcohol can be used for about three months after opening.
2.
Even sterile preparations cannot guarantee their sterility once opened and exposed to the general environment.

Reply Date: 2019/04/24

More Info


When it comes to the use of unsealed 75% alcohol, there are several important considerations regarding its safety, efficacy, and shelf life.
1. Can You Still Use Unsealed 75% Alcohol?
If the bottle of 75% alcohol was left unsealed, it is generally still safe to use, provided that it has not been contaminated. Alcohol is a potent disinfectant and has antimicrobial properties, which means it can kill a wide range of bacteria and viruses. However, if the alcohol was left open for an extended period, there is a risk that it may have absorbed moisture from the air, which could dilute its concentration. A concentration of 60% to 90% alcohol is optimal for disinfection, so if the concentration has dropped significantly below 75%, its effectiveness may be compromised.
Additionally, while alcohol can kill many pathogens, it is not effective against all types of bacteria and viruses, particularly some spores. If you notice any visible contaminants or if the alcohol has an unusual odor, it is best to err on the side of caution and dispose of it.

2. Shelf Life of Opened Alcohol
The shelf life of opened alcohol can vary depending on several factors, including the storage conditions and the type of container. Generally, if stored in a cool, dark place and kept tightly sealed, 75% alcohol can last for several months to a year after opening. However, once opened, it is advisable to use it within six months to ensure its potency.
Alcohol does not spoil in the traditional sense, but its effectiveness can diminish over time due to evaporation and contamination. To maximize its shelf life, always ensure that the cap is tightly sealed after each use and store it away from direct sunlight and heat sources.

3. Safety Tips
- Storage: Keep alcohol in a cool, dry place away from heat sources and direct sunlight. This helps maintain its concentration and effectiveness.

- Sealing: Always ensure that the bottle is tightly sealed after use to prevent evaporation and contamination.

- Check for Contamination: Before using, inspect the alcohol for any signs of contamination, such as cloudiness or sediment. If you notice anything unusual, it’s best to discard it.

- Use Properly: When using alcohol for disinfection, apply it to surfaces and allow it to sit for at least 30 seconds to ensure effective microbial kill.

- Keep Away from Children: Store alcohol out of reach of children to prevent accidental ingestion, which can be harmful.

In summary, unsealed 75% alcohol can still be used if it appears uncontaminated and has been stored properly. However, for optimal effectiveness, it is best to use it within a few months of opening. Always prioritize safety and proper storage practices to ensure that the alcohol remains effective as a disinfectant. If in doubt, it’s better to replace it with a new bottle.

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