High-Risk HPV: Key Insights and Recommendations for Men - Obstetrics and Gynecology

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High-risk HPV infection


Hello, doctor.
I see that you've answered some questions about HPV, so I would like to ask a few as well.
I am a male, and I recently underwent HPV typing tests, which revealed that I am infected with HPV type 53.

1.
Aside from getting the cervical cancer vaccine and practicing safe sex, what other recommendations do you have for me? For example, how long should I wait before getting re-tested?
2.
Can HPV genotyping tests detect latent viruses? Does "latent period" refer to the time from exposure to the virus until a positive test result, or from exposure to the virus until the onset of disease (such as warts or cancerous lesions)?
3.
If I manage to clear the virus through my immune system, is there still a chance I could transmit it to my partner if we engage in unprotected sex afterward?
4.
If I were infected with HPV type 16 but have since cleared the infection, would getting the cervical cancer vaccine afterward provide me with renewed protection against HPV type 16?
5.
The latency period for high-risk HPV can last for several years, or even a lifetime, but most people are able to clear the virus within two years.
Can it be understood that if someone has not engaged in sexual activity for over two years, they are unlikely to test positive for HPV?
6.
I have not had sexual intercourse with anyone for ten years, and I always used condoms during previous sexual encounters.
What can you infer from this? Does it suggest a higher likelihood of environmental transmission, or could it mean that my body has not cleared the virus over the past decade? After all, HPV is primarily transmitted through sexual contact, and the chances of environmental transmission are very low.
This is the question that confuses me the most.
I really do not want to harm my new girlfriend, so I kindly ask for your answers to my questions.
Thank you.

Rong, 30~39 year old female. Ask Date: 2019/07/13

Dr. Huang Jianzhong reply Obstetrics and Gynecology


Infected with HPV type 53.

1.
Aside from getting the cervical cancer vaccine and practicing safe sex, what other recommendations do you have for me? For example, how long should I wait before getting checked again?
Answer: You should get checked again in one year.
2.
Can HPV genotyping tests detect latent viruses? Does "latent period" refer to the time from exposure to the virus until a positive test result, or from exposure to the virus until the onset of disease (such as warts or cancerous lesions)?
Answer: Yes, it can detect latent viruses.
3.
Assuming I have cleared the virus through my own immune response, is there a chance I could transmit it to my partner if we engage in unprotected sex afterward?
Answer: If you have cleared the virus through your immune system, there is no chance of transmitting it to your partner.
4.
If I was infected with HPV type 16 but have since recovered, will getting the cervical cancer vaccine afterward provide me with renewed protection against HPV type 16?
Answer: Yes, it will.
5.
The latency period for high-risk HPV can last for several years, or even a lifetime, but most people are able to clear the virus within two years.
Can we understand that if someone has not engaged in sexual activity for over two years, theoretically, they are unlikely to test positive for HPV?
Answer: Most people can clear the virus within two years.
6.
I have not had sexual intercourse with anyone for ten years, and I always used condoms during previous sexual encounters.
What can the doctor infer from this? Does it suggest a higher likelihood of environmental infection, or does it mean my body has not cleared the virus over the past ten years? After all, HPV is primarily transmitted through sexual contact, and the chance of environmental transmission is very low.
This is what confuses me the most.

Answer: Most people cannot clear the virus on their own.

Reply Date: 2019/07/13

More Info


Understanding High-Risk HPV: Key Insights and Recommendations for Men
Human Papillomavirus (HPV) is a common sexually transmitted infection that can affect both men and women. As a male diagnosed with HPV type 53, it’s understandable to have concerns about your health and the implications for your sexual partners. Let’s address your questions one by one, providing insights and recommendations based on current medical understanding.

1. Recommendations Beyond Vaccination and Safe Sex: While receiving the HPV vaccine (such as Gardasil) is an excellent preventive measure, maintaining a healthy lifestyle can also support your immune system. This includes a balanced diet rich in fruits and vegetables, regular exercise, adequate sleep, and stress management. Regular check-ups with your healthcare provider are essential. Generally, follow-up HPV testing is recommended every 6 to 12 months, but your doctor can provide personalized advice based on your situation.

2. HPV Testing and Latency: HPV testing can detect the presence of the virus, but it does not specifically indicate whether the virus is in a latent (inactive) state. The latency period refers to the time from initial infection to the detection of the virus (which can be weeks to years) and the time from infection to the development of any associated diseases (like genital warts or cancer), which can take much longer. Therefore, a positive test indicates that the virus is present, but it doesn’t clarify when you were infected.

3. Transmission After Clearance: If your immune system successfully clears the HPV infection, the risk of transmitting the virus to a partner is significantly reduced. However, it’s important to note that some strains of HPV can remain dormant in the body, and there is still a potential risk of transmission if the virus reactivates. Engaging in safe sex practices, including the use of condoms, is advisable to minimize any risk.

4. Vaccination After Infection: If you have previously been infected with HPV type 16 and have cleared the infection, receiving the HPV vaccine can still provide additional protection against other strains of the virus. However, the vaccine may not prevent re-infection with the same strain if it were to reactivate. The vaccine is most effective when given before the onset of sexual activity.

5. Understanding HPV Clearance: It’s true that many individuals can clear HPV infections within two years. If you have not engaged in sexual activity for an extended period, it is possible that your body has cleared the virus, which is why you may not test positive. However, if you have a history of HPV infection, it’s also possible that the virus could remain dormant.

6. Potential Sources of Infection: Given your history of consistent condom use and limited sexual partners, it is more likely that your HPV infection could have originated from a previous partner rather than from environmental sources. HPV is primarily transmitted through skin-to-skin contact during sexual activity, and while environmental transmission is theoretically possible, it is quite rare.

In conclusion, while the diagnosis of HPV can be concerning, it’s important to remember that many individuals with HPV do not develop serious health issues. Maintaining open communication with your partner about your HPV status, practicing safe sex, and following up with your healthcare provider for regular screenings are crucial steps in managing your health. If you have further questions or concerns, don’t hesitate to reach out to a healthcare professional for personalized advice.

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