Patients with hepatitis B experience a noticeable increase in hair loss?
Hello Doctor, I have some questions to ask you! My father is 63 years old and is a hepatitis B patient.
He underwent gallbladder removal surgery five years ago and is currently taking Baraclude (entecavir) to control the virus.
Recently, we noticed a significant amount of hair on the bathroom floor after he showers, and family members have also observed an increase in the amount of hair loss from his legs.
I am wondering if this symptom could be a side effect of the hepatitis B medication, a characteristic of the hepatitis B disease itself, or possibly due to another underlying condition?
Jihua, 20~29 year old female. Ask Date: 2019/08/23
Dr. Chen Shidian reply Gastroenterology and Hepatology
There have been no reports of this side effect yet.
Reply Date: 2019/08/23
More Info
Increased hair loss in patients with Hepatitis B can be a multifactorial issue, and it is essential to consider various aspects when evaluating the potential causes. Your father's situation, particularly given his history of Hepatitis B and the medications he is taking, warrants a thorough examination.
Firstly, Hepatitis B itself can lead to systemic effects that may contribute to hair loss. Chronic liver diseases, including Hepatitis B, can disrupt the body's hormonal balance and nutrient absorption, both of which are crucial for healthy hair growth. The liver plays a vital role in metabolizing hormones, and any dysfunction can lead to alterations in androgen levels, which may exacerbate hair loss. Additionally, liver disease can lead to deficiencies in essential nutrients such as zinc and biotin, which are important for hair health.
Secondly, the medication your father is taking, Baraclude (entecavir), is an antiviral drug used to treat Hepatitis B. While it is generally well-tolerated, some patients report side effects, including fatigue and gastrointestinal issues. However, hair loss is not commonly listed as a direct side effect of Baraclude. It is crucial to differentiate between hair loss caused by the medication and hair loss due to the underlying liver condition.
Moreover, other factors such as stress, age, and overall health can significantly impact hair loss. At 63 years old, your father may be experiencing age-related hair thinning, which is common in older adults. Stress, whether physical or emotional, can also trigger a type of hair loss known as telogen effluvium, where hair follicles prematurely enter the resting phase of the hair growth cycle, leading to increased shedding.
In addition to these considerations, it is essential to rule out other potential causes of hair loss. Conditions such as thyroid disorders, autoimmune diseases, or even scalp infections can lead to increased shedding. Given your father's symptoms, it may be beneficial for him to consult with a healthcare provider who can perform a comprehensive evaluation, including blood tests to assess liver function, hormone levels, and nutritional status.
If hair loss is significant or concerning, a referral to a dermatologist specializing in hair loss may be warranted. They can conduct a thorough examination of the scalp and hair follicles, and if necessary, perform a scalp biopsy to determine the underlying cause of the hair loss.
In summary, while Hepatitis B and its treatment may contribute to hair loss, it is essential to consider a holistic view of your father's health. Factors such as age, stress, nutritional deficiencies, and other medical conditions may also play a role. A thorough evaluation by a healthcare professional will help identify the underlying cause and guide appropriate management strategies.
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