Impact of Moisture on Supplements: Risks and Effects - Pharmacology

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Continuation #149825 and #149809?


1.
Can shower gel and water near the bottle cap cause dietary supplements to become damp? It depends on whether they have been wet; if they are damp, it will certainly affect the efficacy of the medication.
--> I did not immediately touch the inner wall of the bottle, but the methylcobalamin tablets feel dry when I take them out now.
2.
If the methylcobalamin tablets are not damp, does that mean they have not been affected by moisture?
3.
It is best not to use methylcobalamin that has been dampened or degraded, as it can negatively impact our liver and kidney metabolism, and if it is ineffective, it would be a waste.
Additionally, it places a burden on the liver and kidneys.
Wishing you health and happiness.
--> If they have indeed been damp, how significant is the impact on liver and kidney metabolism? (Because I am uncertain about the moisture exposure.)

Nìmíng, 30~39 year old female. Ask Date: 2019/08/27

Dr. Hou Fangmin reply Pharmacology


Hello: 1.
If the methylcobalamin tablets feel dry when taken out, then it's fine.
2.
If the methylcobalamin tablets are not damp, does that mean they haven't been exposed to moisture? It should be.
3.
If they have indeed been exposed to moisture, how significantly does it affect the metabolism of the liver and kidneys? Aside from being ineffective, it can be harmful to the kidneys and liver, but the extent varies from person to person.
Please confirm again that if they are not damp, then it is certainly fine.

Reply Date: 2019/08/27

More Info


Moisture can significantly impact the efficacy and safety of dietary supplements, including vitamins and minerals. When supplements are exposed to moisture, they can undergo chemical changes that may render them ineffective or even harmful. This is particularly relevant for products like甲鈷胺 (Methylcobalamin), which is a form of vitamin B12.
1. Moisture Exposure: If the cap of a supplement bottle is wet due to shower gel or water, there is a potential risk of moisture entering the bottle. While you mentioned that the甲鈷胺片 (Methylcobalamin tablets) did not feel damp when you touched them, it is essential to understand that moisture can still affect the contents without visible signs. If the tablets were exposed to a humid environment, they could absorb moisture from the air, leading to degradation.

2. Signs of Moisture Damage: If甲鈷胺片 appears clumped together, has changed color, or has an unusual odor, these could be signs of moisture damage. Even if the tablets feel dry, they might have absorbed enough moisture to affect their stability.
3. Health Risks: Using supplements that have been compromised by moisture can pose health risks. When supplements degrade, they may not only lose their intended efficacy but could also produce harmful byproducts. For instance, certain vitamins can become toxic when they break down. The liver and kidneys are primarily responsible for metabolizing and excreting substances from the body. If a degraded supplement is ingested, it can place additional stress on these organs, potentially leading to adverse effects, especially if consumed over time.

4. Impact on Liver and Kidney Function: The liver metabolizes many substances, including vitamins and supplements. If a supplement is degraded, the liver may struggle to process it effectively, leading to an accumulation of potentially harmful substances. Similarly, the kidneys filter waste products from the blood. If a degraded supplement leads to the production of harmful metabolites, it can increase the workload on the kidneys, potentially leading to kidney damage over time.

5. Preventive Measures: To minimize the risk of moisture affecting your supplements, store them in a cool, dry place, and ensure that the lids are tightly sealed after each use. Avoid storing supplements in bathrooms or kitchens where humidity levels can fluctuate.
In conclusion, while your甲鈷胺片 may not feel damp, it is crucial to consider the potential risks associated with moisture exposure. If you suspect that your supplements may have been compromised, it is advisable to err on the side of caution and discontinue use. Always consult with a healthcare professional if you have concerns about the safety and efficacy of your supplements, especially if you have pre-existing health conditions or are taking other medications. Your health and well-being should always be the top priority.

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