Managing Side Effects of Psychiatric Medications: A Guide for Patients - Psychiatry

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Hello, doctor.
My mother, who is 63 years old, has been diagnosed with depression and anxiety, experiencing symptoms such as insomnia, restlessness, and anxiety.
The doctor prescribed her Sertraline 25 mg, Lorazepam 1 mg, and 3 cc of Clonazepam solution to be taken at night, along with one tablet of Quetiapine as needed.
She has been taking these medications for two days, but in the morning, her heart rate was 106, and she experiences shortness of breath while walking, whereas her usual heart rate is around the 80s.
I'm wondering if she can continue taking the medication.
The follow-up appointment is a long wait, and the doctor is very busy.
Thank you.
Should we endure this for a while until she feels better?

Niming, 60~69 year old female. Ask Date: 2019/09/11

Dr. Huang Xiaoxian reply Psychiatry


Hello, the medications you mentioned generally have low side effects and dosages, but among them, Sertraline has a more significant impact.
I suggest that you first discontinue Sertraline and continue with the other medications to see if there is any improvement.
If there is still no improvement, it would be advisable to take your mother to a nearby psychiatric clinic for a follow-up or return to the original healthcare facility for evaluation.
Best wishes to you!

Reply Date: 2019/09/11

More Info


Managing side effects of psychiatric medications can be a challenging aspect of treatment for both patients and their caregivers. In your mother's case, she has been prescribed several medications, including Sertraline (often referred to as "思樂康"), Lorazepam (悠然), and a liquid formulation of another medication, which may be a form of a benzodiazepine or an antidepressant. It's important to understand how these medications work, their potential side effects, and what steps can be taken to manage those side effects effectively.


Understanding the Medications
1. Sertraline (思樂康): This is a selective serotonin reuptake inhibitor (SSRI) commonly used to treat depression and anxiety disorders. It works by increasing serotonin levels in the brain, which can help improve mood and reduce anxiety. Common side effects may include nausea, insomnia, sexual dysfunction, and increased heart rate.

2. Lorazepam (悠然): This medication is a benzodiazepine that is often prescribed for anxiety and sleep disorders. It works by depressing the central nervous system, which can help to alleviate anxiety and promote sleep. However, it can also cause drowsiness, dizziness, and respiratory depression, especially when combined with other CNS depressants.

3. Liquid Medication (易復樂水劑): Without specific details, it's difficult to determine the exact medication, but if it's another form of a benzodiazepine or an antidepressant, it may have similar side effects to those mentioned above.


Managing Side Effects
Given your mother's symptoms of increased heart rate (tachycardia) and shortness of breath after starting these medications, it is crucial to address these side effects promptly. Here are some strategies:
1. Monitor Vital Signs: Keep track of her heart rate and any other symptoms she experiences. A resting heart rate of 106 beats per minute is elevated, especially if her baseline is typically in the 80s. If this persists or worsens, it may require immediate medical attention.

2. Hydration and Nutrition: Ensure she stays well-hydrated and maintains a balanced diet. Sometimes, dehydration or poor nutrition can exacerbate side effects.

3. Gradual Adjustment: If the medications are causing significant side effects, it may be necessary to discuss with her physician the possibility of adjusting the dosage or switching to a different medication. This should be done under medical supervision.

4. Avoiding Stimulants: Encourage her to avoid caffeine and other stimulants, as they can increase heart rate and anxiety levels.

5. Relaxation Techniques: Techniques such as deep breathing exercises, meditation, or gentle yoga can help manage anxiety and may reduce the perception of side effects.

6. Follow-Up with Healthcare Provider: Since you mentioned that follow-up appointments are delayed, consider reaching out to the clinic to see if there are any cancellations or if a telehealth appointment is available. It’s essential to communicate any concerning side effects to her healthcare provider as soon as possible.


When to Seek Immediate Help
If your mother experiences severe symptoms such as chest pain, persistent shortness of breath, or any other alarming signs, it is crucial to seek emergency medical care. These could be signs of a serious reaction to the medications.


Conclusion
Managing the side effects of psychiatric medications is an essential part of treatment. While it may take time for the body to adjust to new medications, persistent or severe side effects should not be ignored. Open communication with healthcare providers is vital to ensure that your mother receives the appropriate care and adjustments to her treatment plan. Encourage her to be patient, but also proactive in seeking help when needed.

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