Exploring the Relationship Between CBD and Parkinson's Disease Relief - Neurology

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CBD and Parkinson's Disease


Hello Doctor, I previously inquired about surgery for Parkinson's disease.
I would like to ask you again about the relationship between CBD and the alleviation of Parkinson's symptoms.
I tried searching online, but the information I found is difficult to verify.
For instance, does using CBD effectively relieve the symptoms of Parkinson's? I came across a video of an elderly man with severe tremors who experienced a temporary cessation of shaking after using CBD.
If CBD can indeed alleviate Parkinson's symptoms, could it potentially reduce the need for other medications, thereby minimizing side effects (such as dyskinesia)? Additionally, is CBD currently legal in Taiwan? The answers I found online are inconsistent.
If it is legal, would a doctor's prescription be required to obtain it? Thank you, Doctor!

Mr. Lin, 30~39 year old female. Ask Date: 2019/10/20

Dr. Hong Weibin reply Neurology


Hello: CBD (Cannabidiol) is a cannabis product that is currently illegal in Taiwan.
There is no rigorous research evidence showing its effectiveness in the treatment of Parkinson's disease.
For the management of dyskinesia associated with Parkinson's disease, treatment typically involves reducing the dosage of levodopa, adding Amantadine, or considering continuous infusion of dopamine agonists (using a pump for apomorphine infusion).
If these approaches are still ineffective, deep brain stimulation (subthalamic nucleus-DBS) may be considered.
Reference: 1.
What’s behind the popularity of CBD, THC, and other cannabis products https://www.bbc.com/ukchina/trad/vert-cap-46450564

Reply Date: 2019/10/20

More Info


The relationship between cannabidiol (CBD) and Parkinson's disease (PD) is an area of growing interest in both the medical community and among patients seeking alternative treatments. Parkinson's disease is a neurodegenerative disorder characterized by motor symptoms such as tremors, rigidity, and bradykinesia (slowness of movement), as well as non-motor symptoms including anxiety, depression, and sleep disturbances.
Research into the effects of CBD on Parkinson's disease is still in its early stages, but there are some promising findings. CBD is a non-psychoactive compound found in cannabis that has been studied for its potential therapeutic effects, including anti-inflammatory, neuroprotective, and anxiolytic properties. Some studies suggest that CBD may help alleviate certain symptoms of Parkinson's disease, particularly in terms of reducing anxiety and improving sleep quality. For instance, a study published in the journal "Frontiers in Pharmacology" indicated that CBD could have neuroprotective effects, potentially slowing the progression of neurodegenerative diseases.

Regarding the specific symptom of tremors, anecdotal evidence, such as the video you mentioned, suggests that some patients experience temporary relief from tremors after using CBD. However, it is essential to note that individual responses to CBD can vary significantly, and what works for one person may not work for another. Additionally, while some patients report a reduction in motor symptoms, rigorous clinical trials are necessary to establish the efficacy and safety of CBD for Parkinson's disease comprehensively.

As for the potential to reduce the use of other medications, such as those that may cause side effects like dyskinesia (involuntary movements), this is a complex issue. While CBD may provide symptomatic relief, it is not a cure for Parkinson's disease, and it should not be viewed as a replacement for conventional treatments without consulting a healthcare professional. The management of Parkinson's disease typically involves a combination of medications, including levodopa and dopamine agonists, which are essential for controlling motor symptoms. Any changes to medication regimens should be made under the guidance of a physician.

In terms of legal status, as of my last knowledge update in October 2023, CBD has been legalized in many regions, including parts of the United States and some countries. However, regulations can vary significantly by location. In Taiwan, the legal status of CBD is still evolving. As of now, CBD products may be available, but they are subject to strict regulations. It is advisable to check with local authorities or healthcare providers for the most current information regarding the legality of CBD and whether a prescription is required for its use.

In conclusion, while there is some evidence suggesting that CBD may help alleviate certain symptoms of Parkinson's disease, more research is needed to confirm its efficacy and safety. Patients should approach CBD as a complementary treatment rather than a primary therapy and should always consult with their healthcare providers before making any changes to their treatment plans. This ensures that they receive personalized advice based on their specific medical history and current medications.

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