Air Bubbles in Insulin Injections: Risks and Concerns - Internal Medicine

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DM issues


Hello Dr.
Ke,
My mother has had diabetes for over twenty years (family history) and has been using insulin for more than five years.
Initially, my father helped her with the injections, but in the past few months, she has learned to inject herself.
However, her technique is incorrect! Recently, she asked me why there is a sound like air when she pushes the plunger at the end of the injection—like a "pop." I realized that she hasn't been expelling the air from the syringe before drawing up the insulin, which is why she hears that "pop" sound.
As I am also studying nursing, I know that air should not be injected into the body.
Although insulin syringes are smaller and the amount of air is not significant, and it is not injected directly into a blood vessel, I am concerned because my mother has been using this method for nearly six months.
I worry about potential cumulative side effects.
Could this be harmful to her heart? Or will the air be absorbed by the tissues or expelled? Currently, my mother is doing well, but I would like to consult a professional for further understanding.
Thank you!

Kedy, 20~29 year old female. Ask Date: 2002/11/19

Dr. Ke Zhengchang reply Internal Medicine


A minimal amount of air injected subcutaneously should be absorbed and is unlikely to cause significant harm to the human body.

Reply Date: 2002/11/19

More Info


When it comes to insulin injections, the presence of air bubbles can indeed raise concerns, especially for individuals who are managing diabetes over a long period. Your mother’s experience of hearing a “pop” sound when injecting insulin suggests that air is being introduced into the syringe, which can happen if the air is not expelled before drawing up the insulin. This is a common mistake, particularly for those who are new to self-injection.

To address your concerns, it's important to understand the implications of injecting air into the body. Generally, small amounts of air injected subcutaneously (under the skin) are not harmful. The body can absorb small air bubbles, and they typically do not cause any significant issues. However, larger volumes of air or air injected directly into a blood vessel can lead to complications, such as an air embolism, which is a serious condition. Fortunately, the insulin syringes used for subcutaneous injections are designed to minimize the risk of injecting air directly into the bloodstream.

In your mother’s case, since she has been injecting insulin with air bubbles for several months, it’s unlikely that she has experienced any cumulative adverse effects. The air that is injected subcutaneously is usually absorbed by the body without causing harm. However, it is essential to ensure that she learns the correct technique for administering her injections to avoid any potential issues in the future.

Here are some key points to consider regarding insulin injection techniques:
1. Expelling Air Bubbles: Before drawing up insulin, it is crucial to expel any air from the syringe. This can be done by holding the syringe with the needle pointing upwards and gently tapping the side to move any air bubbles to the top, then pushing the plunger slightly to expel the air.

2. Injection Technique: Ensure that she is using the correct technique for injecting insulin. This includes selecting the right injection site (such as the abdomen, thigh, or upper arm), rotating sites to prevent lipodystrophy (fatty lumps or pits under the skin), and injecting at the correct angle (usually 90 degrees for subcutaneous injections).

3. Monitoring for Complications: While it is unlikely that injecting small amounts of air will cause harm, it is still important to monitor for any unusual symptoms, such as pain at the injection site, swelling, or signs of infection. If any concerning symptoms arise, she should consult her healthcare provider.

4. Education and Training: It may be beneficial for your mother to receive additional training on insulin injection techniques from a healthcare professional, such as a diabetes educator or a nurse. This can help reinforce proper techniques and address any questions or concerns she may have.

5. Regular Check-ups: Encourage her to have regular check-ups with her healthcare provider to monitor her diabetes management and address any issues related to her insulin injections.

In conclusion, while the presence of air bubbles in insulin injections can be concerning, small amounts injected subcutaneously are generally not harmful. However, it is essential for your mother to adopt proper injection techniques to ensure her safety and the effectiveness of her diabetes management. If you have any further concerns, do not hesitate to reach out to her healthcare provider for personalized advice and support.

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