Does Parkinson's Disease Cause Weight Loss? Symptoms and Solutions - Neurology

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Can Parkinson's disease cause weight loss?


Hello, may I ask if Parkinson's disease causes continuous weight loss? A woman in her 60s is eating normally but is still losing weight, often experiences hiccups (gastroscopy showed no findings), has severe memory decline, her eyelids are inexplicably red, frequently feels stiffness and pain, and suffers from insomnia.
Are these symptoms related to Parkinson's? What should she supplement to prevent further weight loss? Thank you!

Ling, 20~29 year old female. Ask Date: 2019/12/06

Dr. Hong Weibin reply Neurology


Hello: If there is unintentional weight loss, such as losing more than 5% of body weight in one month or 10% within six months, it may be necessary to investigate other causes of weight loss.
The most concerning possibility is malignant tumors, such as lung cancer or colorectal cancer, which are common in Taiwan.
Additionally, certain autoimmune diseases, medications (such as those for Parkinson's disease that may cause gastrointestinal discomfort, nausea, and decreased appetite), chronic inflammation, hyperthyroidism, and depression can also lead to weight loss.
It is advisable to rule out these causes before attributing the weight loss to sarcopenia related to Parkinson's disease (which can result from decreased mobility due to muscle rigidity, leading to a reduction in muscle mass and weight).
It is recommended to regularly monitor and record your loved one's weight, and have a physician evaluate and refer as necessary.

Reply Date: 2019/12/06

More Info


Parkinson's Disease (PD) is a progressive neurodegenerative disorder that primarily affects movement, but it can also lead to a variety of non-motor symptoms, including weight loss. Weight loss in patients with Parkinson's can be attributed to several factors, including changes in metabolism, reduced appetite, difficulty swallowing (dysphagia), and the energy expenditure associated with increased muscle rigidity and tremors.
In your case, the ongoing weight loss despite normal eating habits could be linked to the disease's impact on the body's ability to process food and maintain weight. It's not uncommon for individuals with Parkinson's to experience a decrease in appetite or changes in taste and smell, which can further contribute to weight loss. Additionally, the physical symptoms of Parkinson's, such as stiffness and pain, can make it challenging to engage in regular physical activity, which is essential for maintaining a healthy weight.

Regarding your specific symptoms, the memory decline and the unusual redness of the eyelids could be related to Parkinson's Disease, as cognitive changes and skin issues can occur in some patients. The stiffness and pain you describe are also common symptoms associated with PD, often resulting from muscle rigidity and dystonia.

To address weight loss, it is crucial to focus on nutritional intake. Here are some recommendations:
1. High-Protein Foods: Incorporating high-quality protein sources such as lean meats, fish, eggs, dairy products, legumes, and nuts can help maintain muscle mass and support overall health.

2. Caloric Density: Opt for foods that are high in calories but low in volume, such as avocados, nut butters, and full-fat dairy products. This can help increase caloric intake without requiring large quantities of food.

3. Frequent Small Meals: Eating smaller, more frequent meals throughout the day can help manage appetite and ensure adequate caloric intake.

4. Hydration: Staying well-hydrated is essential, especially if there are issues with swallowing. Smoothies or protein shakes can be a good way to combine hydration with nutrition.

5. Consult a Dietitian: A registered dietitian can provide personalized dietary advice tailored to the specific needs of someone with Parkinson's Disease, considering their symptoms and preferences.

In terms of managing the stiffness and pain, heat therapy (such as warm baths or heating pads) can often provide relief. Gentle stretching and physical therapy can also help improve flexibility and reduce discomfort. It's essential to consult with a healthcare provider or a physical therapist to develop an appropriate exercise plan that accommodates the individual's abilities and limitations.

As for gastrointestinal issues like frequent burping, these can be related to autonomic dysfunction, which is common in Parkinson's patients. If gastrointestinal symptoms persist, further evaluation by a gastroenterologist may be warranted, even if previous endoscopic examinations did not reveal any significant findings.

Lastly, it is crucial to have regular follow-ups with a neurologist or a movement disorder specialist to monitor the progression of Parkinson's Disease and adjust treatment plans as necessary. Cognitive changes, such as memory decline, should also be addressed, as they can significantly impact quality of life. Support groups and counseling can provide emotional support for both the patient and their family, helping to cope with the challenges posed by the disease.

In conclusion, while weight loss can be a concerning symptom of Parkinson's Disease, there are strategies to manage it effectively through dietary adjustments, physical therapy, and regular medical care. Addressing the full spectrum of symptoms, including cognitive and emotional health, is vital for improving overall quality of life.

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