Abnormal Neutrophils and Lymph Nodes: Causes and Concerns - Family Medicine

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Abnormal lymphocytes and neutrophils, along with lymphadenopathy?


Hello Doctor, I visited the obstetrics and gynecology department in mid-November due to adenomyosis and endometriosis.
The gynecologist ordered blood tests to assess whether I had anemia and if I was suitable for treatment with the Mirena IUD.
The results showed that my white blood cells and red blood cells were normal, but there were two abnormalities: neutrophils at 76.9% and lymphocytes at 16.7%.
Could these abnormalities be related to inflammation caused by endometriosis, or could they indicate an immune deficiency disease? T_T Additionally, last month I developed a small lump in my groin that was initially painful, but it has not disappeared after more than a month and is no longer painful.
Now, on the same side of the groin, two more small lumps have appeared that are not connected and are also painless and movable.
I have been experiencing poor sleep, waking up after five to six hours and unable to fall back asleep.
Could the lymph node swelling be due to lowered immunity, or is there a possibility of lymphoma? T-T Is it possible to improve my immune system and have these symptoms disappear? >_< Also, I would like to ask if drinking chicken essence and taking probiotics are effective in boosting immunity?

Nsi321, 20~29 year old female. Ask Date: 2019/12/08

Dr. Hou Angting reply Family Medicine


Hello Ms.
Nsi321, the distribution of white blood cells in the body can vary, so if your white blood cell count is normal, temporary abnormalities in neutrophils and lymphocytes can be monitored without concern.
You may also consult with an obstetrician-gynecologist to address your concerns regarding inflammation related to endometriosis.
As for the lump in your groin, it is recommended that you follow up and have it evaluated at a surgical outpatient clinic.
Wishing you good health.

Reply Date: 2019/12/08

More Info


Understanding abnormal neutrophil and lymphocyte counts, as well as lymph node enlargement, can be complex and often requires a comprehensive evaluation of the patient's clinical history, symptoms, and laboratory findings. In your case, the elevated neutrophil count (76.9%) and decreased lymphocyte count (16.7%) could indeed be influenced by your underlying conditions, such as endometriosis and adenomyosis, which are known to cause inflammation in the body.

Neutrophils are a type of white blood cell that play a crucial role in the immune response, particularly in fighting off infections. An elevated neutrophil count, known as neutrophilia, can occur in response to various factors, including acute inflammation, infection, stress, or even certain medications. In your situation, the inflammation associated with endometriosis may contribute to the increased neutrophil levels. On the other hand, lymphocytes are another type of white blood cell that are vital for the immune system, particularly in fighting viral infections and regulating immune responses. A low lymphocyte count, or lymphopenia, can result from various conditions, including chronic stress, certain infections, autoimmune diseases, or even the effects of medications.

Regarding your concerns about the lymph nodes in your groin area, the presence of small, movable lymph nodes that are not painful is often indicative of a benign process, such as a reactive lymphadenopathy. This can occur in response to localized infections or inflammation, which may be related to your endometriosis or other factors. However, the persistence of these lymph nodes warrants monitoring, especially if they change in size, consistency, or if new symptoms develop.

It is important to note that while lymphadenopathy can be associated with malignancies, such as lymphoma or metastatic disease, the likelihood of such conditions is generally lower when the lymph nodes are small, movable, and non-tender. Nevertheless, if there are any concerning features or if your symptoms worsen, further evaluation, including imaging studies or a biopsy, may be warranted.

As for your concerns about immune function and the potential for immune deficiency diseases, it is essential to consider that various factors can influence immune health, including chronic stress, sleep disturbances, and underlying medical conditions. Poor sleep can indeed affect immune function, leading to a decreased ability to respond to infections and inflammation. Therefore, addressing sleep issues may be beneficial for your overall health and immune function.

Regarding your question about boosting immunity through dietary supplements like chicken essence and probiotics, there is some evidence to suggest that certain probiotics can support immune health by promoting a balanced gut microbiome, which plays a crucial role in immune function. However, the effectiveness of chicken essence specifically in boosting immunity is less clear and may vary from person to person. A balanced diet rich in fruits, vegetables, whole grains, lean proteins, and healthy fats is generally recommended to support overall health and immune function.

In conclusion, while your current lab findings and symptoms may be concerning, they can often be explained by your underlying conditions. It is essential to maintain regular follow-ups with your healthcare provider, who can monitor your symptoms and lab results over time. If you experience any new symptoms or changes in your health, do not hesitate to seek medical attention. Additionally, focusing on lifestyle factors such as improving sleep quality, managing stress, and maintaining a healthy diet can contribute positively to your overall well-being.

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