Medication Safety During Pregnancy: Effects on Fetal Movement - Obstetrics and Gynecology

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Medications during pregnancy


Hello, doctor.
I am the one who inquired about medication for pregnant women the day before yesterday.
I visited an ENT specialist who sprayed (wanose) in my nose.
I would like to ask you about something.
During this period, I have noticed decreased fetal movement, but after using the spray that night, the baby moved a lot and for a long time.
However, yesterday and today, the fetal movement has decreased again, similar to before.
I would like to know if the increased fetal movement on the day I used the spray was due to the vasoconstrictive components in the medication causing discomfort to the baby.
Could the ingredients in the spray make the baby uncomfortable? Will it affect the umbilical cord and placenta's ability to supply oxygen to the baby? I am currently 34 weeks pregnant.

Xun, 30~39 year old female. Ask Date: 2019/12/30

Dr. Huang Jianzhong reply Obstetrics and Gynecology


During this time, I have noticed less fetal movement, but after using that medication the other night, the baby moved a lot and for a long time.
However, yesterday and today, the fetal movement has decreased again, similar to before.
I would like to ask the doctor if the increased fetal movement on the day I used the medication was due to the vasoconstrictive components in the medication making the baby uncomfortable.
Could the ingredients in the medication cause discomfort to the baby? Would it affect the umbilical cord and placenta's ability to supply oxygen to the baby? I am currently 34 weeks pregnant.

Answer: It should not be a concern.

Reply Date: 2019/12/30

More Info


When it comes to medication safety during pregnancy, particularly concerning fetal movement, it is crucial to understand how various medications can affect both the mother and the developing fetus. Your inquiry about the nasal spray (wanose) and its potential effects on fetal movement is valid, especially at 34 weeks of gestation, a time when fetal activity can be closely monitored.

Firstly, it is essential to recognize that fetal movement is a significant indicator of the baby's well-being. Changes in fetal movement patterns can be influenced by several factors, including the mother's activity level, hydration status, and even the medications she may be taking. In your case, you noticed increased fetal movement after using the nasal spray, followed by a return to less frequent movement. This fluctuation can be concerning, but it is not uncommon.

The active ingredient in many nasal sprays, including those that cause vasoconstriction (narrowing of blood vessels), can lead to temporary changes in blood flow. While these medications are generally considered safe during pregnancy, their effects can vary. Vasoconstriction could theoretically lead to a transient reduction in blood flow to the uterus, which might cause the fetus to react by moving more vigorously. However, this is not a direct indication of distress; rather, it may be a response to changes in the uterine environment.

Regarding your concerns about whether the medication could make the baby uncomfortable or affect the umbilical cord and placenta's ability to supply oxygen, it is essential to note that most nasal sprays, when used as directed, do not significantly impact placental blood flow or oxygen delivery to the fetus. The placenta is designed to protect the fetus from many substances, and while some medications can cross the placental barrier, the effects are often minimal and not harmful when used appropriately.

The FDA categorizes medications based on their safety during pregnancy. For instance, many nasal sprays are classified as Category B, indicating that animal reproduction studies have not demonstrated a risk to the fetus, but there are no adequate and well-controlled studies in pregnant women. It is always advisable to consult with your healthcare provider regarding the specific medication you are using, as they can provide tailored advice based on your medical history and the specifics of your pregnancy.

If you continue to notice significant changes in fetal movement, it is crucial to monitor these changes closely. A decrease in fetal movement, especially after 28 weeks, should prompt a discussion with your healthcare provider. They may recommend a non-stress test or ultrasound to ensure that the baby is healthy and receiving adequate oxygen.

In summary, while the nasal spray you used may have led to temporary changes in fetal movement, it is unlikely to have caused any harm to your baby. However, maintaining open communication with your healthcare provider is vital. They can help you navigate any concerns regarding medication use during pregnancy and monitor your baby's health effectively. Always prioritize your well-being and that of your baby by seeking professional guidance when in doubt.

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