Appendiceal Submucosal Tumors: Surgical Approaches and Considerations - Surgery

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Submucosal tumor of the appendix?


Doctor, I recently underwent a colonoscopy and a tumor approximately 2 cm in size was found in the cecum.
At that time, only a biopsy was performed and no removal was done because the doctor believed that the wall of the cecum was thinner, and removal would pose a risk.
The biopsy results were benign, but since the doctor could not confirm whether there were any abnormalities in the submucosa, a CT scan was recommended for further evaluation, and I was subsequently referred to a colorectal surgeon.
The surgeon's recommendation is to remove the right colon, as there is concern that if only the cecum is removed and the pathology results show malignancy, a second surgery would be necessary.
Is this approach standard practice in the medical community? After all, it seems excessive to perform such a significant organ resection for what could potentially be a benign tumor.
Additionally, why can't the doctor use techniques like EMR (Endoscopic Mucosal Resection) or ESD (Endoscopic Submucosal Dissection) to manage this tumor endoscopically?

Flack, 30~39 year old female. Ask Date: 2020/03/03

Dr. Yu Mingchang reply Surgery


Hello; it is possible to first perform an appendectomy and send the tissue for frozen section examination during the procedure.
If acute appendicitis is confirmed, then a colectomy may be considered.
The Ministry of Health and Welfare Changhua Hospital cares about you.

Reply Date: 2020/03/03

More Info


Understanding appendiceal submucosal tumors, particularly in the context of surgical approaches and considerations, is crucial for effective management and patient outcomes. Your situation, where a 2cm tumor was identified in the cecum during a colonoscopy, raises several important points regarding diagnosis, treatment options, and the rationale behind surgical decisions.

Firstly, it is essential to understand that submucosal tumors of the appendix can vary significantly in their nature, ranging from benign lesions like lipomas or neurofibromas to malignant tumors such as carcinoid tumors or even more aggressive forms. The initial biopsy indicating a benign result is a positive sign; however, the concern regarding the potential for malignancy, especially given the tumor's submucosal location, is valid. Submucosal tumors can sometimes be deceptive, as they may not exhibit typical features of malignancy on imaging or initial biopsy.

The decision to perform a more extensive surgical procedure, such as a right hemicolectomy, rather than just an appendectomy, is often based on several factors. One primary consideration is the risk of an undetected malignancy. If the tumor were to be malignant, a more extensive resection may be necessary to ensure complete removal and to prevent recurrence. This is particularly relevant in cases where the tumor's characteristics are uncertain, and there is a potential for aggressive behavior.
In standard medical practice, if there is a significant concern for malignancy, especially in a submucosal tumor, a more conservative approach may not be sufficient. The rationale behind performing a right hemicolectomy instead of just an appendectomy is to minimize the risk of needing a second surgery if malignancy is confirmed later. This approach is often considered a standard practice in cases where the tumor's nature is ambiguous, and the potential for malignancy exists.

Regarding the use of endoscopic techniques such as Endoscopic Mucosal Resection (EMR) or Endoscopic Submucosal Dissection (ESD), these methods are typically reserved for lesions that are more superficial and can be safely removed without significant risk of complications. In the case of a submucosal tumor, especially one located in the appendix, the risk of perforation or incomplete resection is higher. The anatomy of the appendix and the potential for complications during endoscopic procedures make these techniques less favorable for deeper lesions.
In conclusion, the surgical approach recommended by your physician aligns with standard medical practices when dealing with uncertain appendiceal tumors. While the idea of performing a more extensive surgery for a potentially benign tumor may seem excessive, it is often a necessary precaution to ensure comprehensive treatment and to mitigate the risk of future complications. It is always advisable to discuss these concerns with your healthcare provider, who can provide personalized insights based on your specific case and the latest medical guidelines. Regular follow-ups and imaging studies will also be essential in monitoring your condition post-surgery.

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