Liver Function Tests: What Your ALT and AST Levels Mean

Liver function inquiry?

Hello Dr.
Chen, my blood test results show an ALT of 47 and an AST of 24.
Three months ago and six months ago, my ALT levels were 61 and 45, respectively.
The doctor also tested for hepatitis B and C, and there were no issues.
I would like to ask if these numbers are concerning.
Although the doctor advised me to exercise more, as my ALT has decreased from 61 to 47, it is still above 35.
Should I continue taking the liver protection medication, the red capsules, since my levels are no longer in the 60s? I still have some left from the previous prescription.
Thank you for your response, doctor.

Xing, 20~29 year old female. Ask Date: 2020/03/05

Dr. Chen Shidian reply Gastroenterology and Hepatology

Liver-protective medications may not be necessary, but it is important to actively lose weight, primarily through dietary control (reducing caloric intake) and supplemented by exercise, aiming for a weight loss of 3-5%.

Reply Date: 2020/03/05

More Info

Understanding liver function tests, particularly the significance of ALT (alanine aminotransferase) and AST (aspartate aminotransferase) levels, is crucial for assessing liver health. Your recent blood test results show an ALT level of 47 and an AST level of 24. While your ALT level is above the normal range (typically 10-40 U/L), your AST level is within the normal range (10-42 U/L).
ALT is primarily found in the liver, and elevated levels often indicate liver cell injury or inflammation. Conversely, AST is found in various tissues, including the liver, heart, and muscles, and its elevation can be due to liver issues or other conditions affecting these organs. In your case, the ALT level is concerning as it indicates some degree of liver stress or damage, but the fact that it has decreased from 61 to 47 over the past few months is a positive sign. This reduction suggests that whatever was causing the elevation may be improving, possibly due to lifestyle changes such as increased physical activity.

It's important to note that while your ALT level is elevated, it is not alarmingly high. Levels can vary significantly based on various factors, including diet, exercise, alcohol consumption, and underlying health conditions. Your doctor’s recommendation to engage in more physical activity is sound advice, as regular exercise can help improve liver function and overall health. Additionally, maintaining a balanced diet, avoiding alcohol, and managing weight are critical components of liver health.

Regarding the liver supplement you mentioned, it is essential to consult your physician before continuing any medication or supplement, especially if your ALT levels are improving. If your doctor prescribed the supplement when your ALT was significantly higher, it may have been intended to support liver health during a period of elevated liver enzymes. However, since your levels have decreased, your doctor may reassess the need for the supplement. It’s always best to follow your healthcare provider's guidance on whether to continue or discontinue any medication or supplement.

In summary, while your ALT level is elevated, the trend of improvement is encouraging. Continue to follow your doctor's advice regarding lifestyle changes and regular monitoring of your liver function tests. If you have any concerns or if your symptoms change, do not hesitate to reach out to your healthcare provider for further evaluation and guidance. Regular follow-ups and proactive management are key to maintaining liver health and preventing potential complications.

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