the Side Effects of KanKen for Heart Patients - Cardiology

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Hello, Doctor: I am a patient with 30 years of bronchiectasis (in both lower lungs).
I have hypertension and take half of a 5 mg dose of Concor.
Recently, I have been experiencing persistent chest tightness.
I noticed that Concor has side effects related to asthma; should I avoid taking it?

Li Rongjun, 60~69 year old female. Ask Date: 2020/03/12

Dr. He Dongjin reply Cardiology


Hello, it may be possible to temporarily pause and observe if the symptoms improve.
If the chest tightness resolves, you can consult your attending physician to adjust the medication.
Changhua Hospital cares about you.

Reply Date: 2020/03/12

More Info


Hello, thank you for your question regarding the use of KanKen (Concor) in the context of your existing bronchial dilation condition and recent symptoms of chest tightness. It’s important to understand both the benefits and potential side effects of any medication, especially for patients with pre-existing conditions like yours.

KanKen, which contains the active ingredient bisoprolol, is a beta-blocker primarily used to manage high blood pressure and certain heart conditions. While it is effective in reducing heart rate and controlling blood pressure, it can also have side effects that may impact patients with respiratory conditions, such as asthma or chronic obstructive pulmonary disease (COPD).

One of the known side effects of beta-blockers, including KanKen, is bronchoconstriction, which can exacerbate asthma symptoms or lead to breathing difficulties in susceptible individuals. This is particularly concerning for patients with a history of bronchial issues, as you mentioned having bronchial dilation disease for 30 years. If you are experiencing increased chest tightness or difficulty breathing, it is crucial to evaluate whether KanKen is contributing to these symptoms.

Here are some considerations regarding your situation:
1. Monitoring Symptoms: If you notice that your chest tightness correlates with the initiation or dosage increase of KanKen, it may be worth discussing this with your healthcare provider. Keeping a symptom diary can help identify any patterns related to your medication.

2. Consulting Your Doctor: It is essential to communicate openly with your physician about your symptoms. They may consider adjusting your medication regimen, switching to a different antihypertensive that has a more favorable profile for patients with respiratory issues, or possibly prescribing a bronchodilator to help manage any respiratory symptoms.

3. Potential Alternatives: There are other classes of antihypertensive medications that may be more suitable for individuals with respiratory conditions. For example, calcium channel blockers or certain ACE inhibitors might be options to explore, as they typically do not have the same bronchoconstrictive effects as beta-blockers.

4. Lifestyle Modifications: In addition to medication adjustments, lifestyle changes can also play a significant role in managing both hypertension and respiratory health. Regular exercise, a balanced diet, and avoiding known triggers (such as allergens or irritants) can help improve your overall condition.

5. Emergency Situations: If you experience severe shortness of breath, wheezing, or any acute respiratory distress, seek immediate medical attention. It is crucial to address any potential exacerbation of your bronchial condition promptly.

In summary, while KanKen can be effective for managing high blood pressure, its potential side effects, particularly in patients with respiratory conditions, warrant careful consideration. It is vital to have an ongoing dialogue with your healthcare provider to ensure that your treatment plan is safe and effective for your specific health needs. Your well-being is the priority, and adjustments to your medication may be necessary to achieve optimal health outcomes.

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