Chlamydia Symptoms and Treatment: A Patient's Journey - Urology

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The laboratory test showed Chlamydia IgG1: 64X(+) but IgA was negative.
The gonorrhea PCR was negative.
The only sexual encounter was on January 15, and I experienced symptoms of chlamydia.
On February 22, I saw a doctor, and the urine test was normal.
However, the doctor prescribed anti-inflammatory coated tablets and doxycycline for 7 days, but I still felt uncomfortable after finishing the medication.
When I pressed on the urethra, there was transparent discharge.
Therefore, on March 9, I saw the doctor again, and the urine test was still normal.
This time, I paid out of pocket for a dose of ceftriaxone and took erythromycin for 7 days.
Today is the fourth day, and pressing on the urethra no longer produces discharge, but I still see discharge at the urethral opening.
Urination is painless, but there is occasional mild stinging at the urethral opening.

1.
Is this due to inflammation of the urethral opening, the recovery period, or because the treatment is not yet complete? If the symptoms persist after completing the medication, should I return for a follow-up?
2.
After two treatments, there is still transparent discharge at the urethral opening.
Does this suggest that it may not be caused by chlamydia? Online information indicates that chlamydia should theoretically be resolved within two weeks.
Thank you, doctor, for taking the time to respond.

Yiwun, 20~29 year old female. Ask Date: 2020/03/13

Dr. Li Xinyi reply Urology


The symptoms you mentioned could be caused not only by Chlamydia but also by Trichomoniasis or a urinary tract infection that may affect the prostate.
It is advisable to return to the urology department for further examination and to discuss with your physician.

Reply Date: 2020/03/13

More Info


Understanding Chlamydia Symptoms and Treatment: A Patient's Journey
It sounds like you have been through quite a journey regarding your health, particularly concerning the diagnosis and treatment of a Chlamydia infection. Chlamydia is a common sexually transmitted infection (STI) caused by the bacterium Chlamydia trachomatis. It often presents with mild or no symptoms, which can lead to complications if left untreated. Your experience highlights the importance of thorough testing and follow-up care when dealing with STIs.

From your description, you initially tested positive for Chlamydia IgG antibodies, which indicates a past infection, while your IgA was negative, suggesting that there might not be an active infection at that time. The negative PCR test for gonorrhea is also a good sign, as it rules out another common STI that can occur alongside Chlamydia. The timeline of your symptoms and treatments is crucial for understanding your current situation.

You mentioned that after your first treatment with doxycycline and anti-inflammatory medication, you still felt discomfort, including the presence of clear discharge when you pressed on the urethra. This could indicate several things. First, the presence of discharge could be due to residual inflammation in the urethra, which might take time to resolve even after the infection has been treated. It is also possible that the initial treatment did not fully eradicate the infection, or that there is another underlying issue that needs to be addressed.

Regarding your questions:
1. Urethral Inflammation and Recovery: The mild stinging sensation and the presence of discharge could indeed be signs of urethral inflammation. This inflammation can persist even after the infection has been treated, especially if there was significant irritation or if the urethra was inflamed prior to treatment. It is also possible that you are still in the recovery phase, and it may take some time for the symptoms to completely resolve. If you have completed your treatment and symptoms persist, it is advisable to return to your healthcare provider for further evaluation. They may consider additional tests to rule out other infections or conditions, such as non-gonococcal urethritis (NGU), which can be caused by other organisms.

2. Persistent Symptoms and Differential Diagnosis: The fact that you have undergone two rounds of treatment and still experience discharge raises the question of whether the symptoms are indeed due to Chlamydia. While Chlamydia is typically treatable with the right antibiotics, other infections or conditions could be at play. For example, urethritis can be caused by other bacteria, viruses, or even irritants. It’s also worth noting that some patients may experience post-infectious symptoms that can mimic an ongoing infection even after successful treatment.
In summary, while it is encouraging that your symptoms have improved, the presence of discharge and mild discomfort suggests that further investigation may be warranted. It is essential to maintain open communication with your healthcare provider, who can guide you through the next steps, which may include additional testing or a referral to a specialist if necessary.
In the meantime, ensure you are practicing safe sex and consider informing any sexual partners about your situation, as they may need to be tested and treated as well to prevent reinfection. Remember, STIs are common, and seeking treatment is a responsible step towards maintaining your health and the health of others.

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