If my husband tested positive for Mediterranean, does that mean he does not have Mediterranean?
My husband underwent testing to check for Mediterranean anemia, and the result was positive.
Does this mean he does not have Mediterranean anemia?
Wei Hongjie, 30~39 year old female. Ask Date: 2020/04/09
Dr. Chen Liqin reply Obstetrics and Gynecology
Sorry, I cannot interpret based on your description.
Please consult a laboratory physician directly to determine if it is "abnormal" or if you are a "carrier." Dr.
Chen Li-Chin, Obstetrician and Gynecologist, Nantou Hospital.
Reply Date: 2020/04/09
More Info
A positive Mediterranean test, often referred to in the context of Mediterranean anemia or thalassemia screening, does not indicate that your husband does not have the condition. In fact, a positive result typically suggests that he may carry a gene associated with a form of thalassemia or another hemoglobinopathy, which is common in individuals of Mediterranean descent, as well as in other populations.
To clarify, thalassemia is a genetic blood disorder characterized by the body’s inability to produce sufficient hemoglobin, leading to anemia. The Mediterranean test is a screening tool used to identify carriers of thalassemia or other related disorders. A positive result indicates that your husband may be a carrier of the gene for thalassemia, but it does not confirm that he has the disease itself.
If your husband has a positive Mediterranean test, it is essential to follow up with a healthcare provider for further evaluation. This may include additional blood tests, such as a complete blood count (CBC) and hemoglobin electrophoresis, which can provide more detailed information about his hemoglobin types and levels. These tests can help determine whether he is a carrier or if he has a more severe form of thalassemia.
It is also important to consider family history and any symptoms that may be present. Carriers of thalassemia often do not exhibit symptoms, but if both parents are carriers, there is a risk that their children could inherit the condition. Genetic counseling may be beneficial for couples who are carriers, especially if they are planning to have children.
In summary, a positive Mediterranean test does not mean that your husband does not have thalassemia; rather, it suggests that he may carry a gene associated with the disorder. Further testing and consultation with a healthcare professional are necessary to understand the implications of the test result fully. It is crucial to approach this situation with a clear understanding of the condition, the testing process, and the potential next steps for diagnosis and management.
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