Interactions of Emergency Contraceptive Pills with Other Medications
Hello, doctor! My girlfriend has been taking oral contraceptives regularly, and she recently developed a bacterial infection.
The doctor prescribed griseofulvin and desloratadine.
Will this affect the effectiveness of her birth control? After completing these medications, when can we have unprotected sex?
Zeng Yuxing, 20~29 year old female. Ask Date: 2020/04/28
Dr. Zhang Kunmin reply Obstetrics and Gynecology
Hello,
Medications that may interact with oral contraceptives include:
1.
Antibiotics (Penicillin, Cephalosporins, Erythromycin, Sulfonamides, Bactrim, Chloramphenicol) - These may reduce the intestinal flora that aids in absorption, thereby decreasing the effectiveness of contraceptives.
2.
Sedatives (Barbiturates) - These can increase the metabolism of contraceptives, reducing their effectiveness.
3.
Antiepileptic drugs (Primidone, Phenytoin, Carbamazepine) - These also increase the metabolism of contraceptives, leading to decreased effectiveness.
4.
Antituberculosis medications (Rifampicin, Isoniazid).
5.
Antidiabetic medications (Rosiglitazone).
6.
Acetaminophen and Ascorbic acid (Vitamin C) - These may inhibit the metabolism of estrogen, potentially increasing its concentration in the body and leading to a higher incidence of side effects.
7.
Oral contraceptives can affect the action of anticoagulants.
8.
Smoking - This can increase the metabolism of contraceptives, reducing their effectiveness.
It is recommended to wait until the next cycle for contraceptive effectiveness to be restored.
Thank you! Wishing you peace and health.
Dr.
Zhang
Reply Date: 2020/04/28
More Info
The interaction between antibiotics and birth control pills is a topic of significant concern for many women who rely on hormonal contraceptives for pregnancy prevention. In your case, your girlfriend is taking birth control pills regularly and has been prescribed griseofulvin and desloratadine for a bacterial infection. Let's explore whether these medications could potentially affect the efficacy of her birth control.
First, it is essential to understand how antibiotics can interact with hormonal contraceptives. Historically, certain antibiotics, particularly those in the penicillin and tetracycline families, have been thought to reduce the effectiveness of birth control pills. This is primarily due to the possibility that antibiotics may disrupt the gut flora, which plays a role in the metabolism and absorption of the hormones in birth control pills. However, most recent studies and guidelines indicate that the majority of antibiotics do not significantly impact the effectiveness of hormonal contraceptives.
Griseofulvin, which is an antifungal medication used to treat skin infections caused by fungi, is not classified as an antibiotic that typically interacts with birth control pills. According to current medical literature, griseofulvin does not have a known effect on the efficacy of hormonal contraceptives. Therefore, your girlfriend should be able to continue relying on her birth control pills without concern for reduced effectiveness while taking griseofulvin.
On the other hand, desloratadine is an antihistamine used primarily for the treatment of allergies. It does not have any known interactions with birth control pills and is not expected to affect their efficacy. Thus, both medications prescribed to your girlfriend should not interfere with her birth control.
Regarding your question about when it is safe to have unprotected intercourse after completing these medications, it is generally advisable to wait until she has completed her course of antibiotics and has taken her birth control pills consistently for at least seven days. This precaution helps ensure that her hormone levels are stable and that she is fully protected against pregnancy.
In summary, neither griseofulvin nor desloratadine should affect the effectiveness of your girlfriend's birth control pills. However, it is always a good practice to consult with her healthcare provider for personalized advice, especially if she has any concerns about her medications or contraceptive methods. Additionally, maintaining open communication about contraceptive use and any changes in medication is crucial for ensuring effective pregnancy prevention.
In conclusion, while certain antibiotics can impact the effectiveness of birth control pills, the medications your girlfriend is currently taking do not fall into that category. As long as she continues to take her birth control pills as directed, she should remain protected against pregnancy. If there are any uncertainties or if she experiences any side effects, it is best to consult her healthcare provider for further guidance.
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