Impact of Birth Control Pills on Cholesterol Levels: Key Questions Answered - Obstetrics and Gynecology

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Side effects of contraceptive pills?


Hello, doctor.
I have been taking oral contraceptives for a year, and during my health check-up in March, I found out that my cholesterol levels were elevated.
I stopped taking the oral contraceptives in March.
I would like to ask the doctor: 1.
Do oral contraceptives affect cholesterol levels? 2.
If cholesterol levels are elevated, can I still use oral contraceptives? 3.
If I switch to an intrauterine device (IUD), will it have a lesser impact on cholesterol levels? Thank you, doctor!

Niming, 20~29 year old female. Ask Date: 2020/04/28

Dr. Cao Guotao reply Obstetrics and Gynecology


Hello, contraceptive pills can increase cholesterol levels.
If they are elevated, switching to an intrauterine device (IUD) can eliminate this issue.
Wishing you good health.

Reply Date: 2020/04/28

More Info


The impact of birth control pills on cholesterol levels is a significant concern for many women, especially those who may already have elevated cholesterol levels or other cardiovascular risk factors. Let's address your questions one by one.

1. Do birth control pills affect cholesterol levels?
Yes, hormonal contraceptives, including birth control pills, can influence lipid metabolism, which includes cholesterol levels. Estrogen, a key hormone in many birth control pills, can lead to an increase in high-density lipoprotein (HDL) cholesterol, often referred to as "good" cholesterol. However, it can also lead to an increase in triglycerides and low-density lipoprotein (LDL) cholesterol, which is considered "bad" cholesterol. The extent of these changes can vary based on the specific formulation of the pill, the dosage of hormones, and individual patient factors such as genetics, diet, and lifestyle.

2. If cholesterol is elevated, can I still take birth control pills?
If you have elevated cholesterol levels, it is crucial to consult with your healthcare provider before resuming or starting any hormonal contraceptive. While some women may tolerate birth control pills without significant issues, others may experience worsening lipid profiles. Your doctor may recommend alternative contraceptive methods that do not contain estrogen, such as progestin-only pills or non-hormonal options, especially if you have other risk factors for cardiovascular disease, such as obesity, smoking, or a family history of heart disease.

3. Would switching to an intrauterine device (IUD) have a lesser impact on cholesterol?
Switching to a hormonal IUD, such as the Mirena or Skyla, may have a different impact on cholesterol levels compared to oral contraceptives. Hormonal IUDs release a lower dose of progestin directly into the uterus, which can lead to fewer systemic hormonal effects than oral contraceptives. This localized delivery may result in a lesser impact on lipid levels, but individual responses can vary. Non-hormonal IUDs, such as the copper IUD, do not affect hormone levels at all and therefore would not influence cholesterol levels.

In addition to considering contraceptive options, it is essential to address lifestyle factors that can help manage cholesterol levels. Regular physical activity, a balanced diet rich in fruits, vegetables, whole grains, and healthy fats, and maintaining a healthy weight can all contribute positively to lipid profiles. If lifestyle modifications are insufficient, your healthcare provider may recommend medications to help manage cholesterol levels.

In summary, hormonal contraceptives can affect cholesterol levels, and if you have elevated cholesterol, it is essential to discuss your options with your healthcare provider. They can help you weigh the benefits and risks of different contraceptive methods based on your individual health profile and family history. Regular monitoring of your cholesterol levels and overall cardiovascular health is also advisable, especially if you are considering hormonal birth control.

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