Comparing Accuracy: CT Scan vs. Ultrasound for Salivary Gland Tumors - Radiology

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Computed Tomography and Ultrasound


Hello Dr.
Wang: Previously, I visited the otolaryngology department at a medical center due to a lump under my right ear.
The physician performed an ultrasound examination and diagnosed it as a 0.9 x 0.6 cm salivary gland tumor, recommending follow-up.
Later, due to enlarged lymph nodes in my jaw, I consulted another hospital where the physician arranged for a CT scan (with contrast injection).
However, the report did not indicate a salivary gland tumor, although I can still feel the lump upon palpation.
I would like to ask: Which imaging modality has a higher accuracy, CT or ultrasound? Is there a possibility of misinterpretation with the CT scan?

Gaga, 40~49 year old female. Ask Date: 2020/05/01

Dr. Wang Yifen reply Radiology


Hello: Imaging examinations such as CT and ultrasound are non-invasive tests.
Their diagnostic accuracy can be influenced by factors such as the nature of the disease (e.g., location, size, tumor characteristics), patient cooperation, body habitus, and the conditions during scanning.
There is a possibility of false negatives or false positives, and they cannot be considered 100% accurate.
It is not possible to definitively state which method has a higher accuracy rate; clinical judgment by a physician is still necessary to determine if additional diagnostic tests are needed.
Please visit an otolaryngologist for further advice.
Wishing you peace and good health.

Reply Date: 2020/05/01

More Info


When it comes to diagnosing salivary gland tumors, both CT scans and ultrasound have their own strengths and weaknesses, and their accuracy can vary based on several factors, including the specific characteristics of the tumor and the experience of the interpreting physician.

Ultrasound (US) is often the first imaging modality used for evaluating salivary gland masses. It is particularly useful because it is non-invasive, does not involve radiation, and can provide real-time imaging. Ultrasound is excellent for assessing the characteristics of a mass, such as its size, shape, and whether it is solid or cystic. It can also help in evaluating the vascularity of the lesion and the surrounding structures. However, ultrasound is operator-dependent, meaning that the accuracy of the diagnosis can significantly depend on the skill and experience of the technician performing the ultrasound and the radiologist interpreting the results.

CT scans, especially when enhanced with contrast, provide a more comprehensive view of the anatomy and can help in assessing the extent of the disease, including involvement of adjacent structures and lymph nodes. CT is particularly useful for evaluating deeper structures that may not be well visualized on ultrasound. However, CT scans involve exposure to ionizing radiation, which is a consideration, especially in younger patients or those requiring multiple follow-ups.

In your case, the discrepancy between the ultrasound findings (which indicated a 0.9 x 0.6 cm parotid gland tumor) and the CT scan (which did not show any salivary gland tumor) raises important questions. It is indeed possible for CT scans to miss small lesions, particularly if they are not enhancing or if they are located in a challenging area. Additionally, the presence of lymphadenopathy in your case could suggest a reactive process or another pathology that may not be directly related to the salivary gland tumor.

Accuracy Comparison: Studies have shown that while ultrasound is very effective for initial evaluation, CT scans tend to have higher sensitivity for detecting larger and more complex lesions. However, smaller tumors, particularly those that are cystic or have low attenuation, may be missed on CT. The accuracy of both modalities can also be influenced by the presence of artifacts, the patient's anatomy, and the specific imaging protocols used.

Potential for Misinterpretation: Yes, there is a possibility of misinterpretation with CT scans. Factors such as overlapping structures, motion artifacts, and the inherent limitations of the imaging technique can lead to false negatives or positives. In your situation, if the CT scan did not reveal the tumor but clinical examination suggested otherwise, further evaluation may be warranted.

Recommendations: Given the conflicting results, it may be beneficial to consider further imaging studies, such as MRI, which can provide additional information about soft tissue structures without the radiation exposure associated with CT. Additionally, if there is a clinical suspicion of a tumor based on physical examination, a biopsy may be necessary to obtain a definitive diagnosis.

In summary, both CT and ultrasound have their roles in the evaluation of salivary gland tumors, and the choice of imaging modality may depend on the clinical context, the characteristics of the lesion, and the need for further evaluation. It is essential to have a multidisciplinary approach, including consultation with specialists in radiology and oncology, to determine the best course of action based on the individual case.

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