the Effectiveness and Interactions of Delian Birth Control - Obstetrics and Gynecology

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Effectiveness of the Second Pack of Oral Contraceptives and Drug Interactions


Hello, doctor.
I would like to ask: 1.
Does metformin have any drug interactions with Dailian, and will it affect the contraceptive effectiveness of Dailian? 2.
Does the second pack of Dailian also need to be taken for the first 7 pills to be effective, or is it effective as soon as the first pill is taken? Thank you.

No, 20~29 year old female. Ask Date: 2020/05/15

Dr. Cao Guotao reply Obstetrics and Gynecology


Hello, generally it does not have an impact; taking birth control pills provides contraceptive effects at any time.
Wishing you good health.

Reply Date: 2020/05/15

More Info


When it comes to understanding the effectiveness and interactions of the Delian birth control pill (which contains cyproterone and ethinylestradiol), it's essential to consider various factors, including potential drug interactions and the timing of the pill's effectiveness.

1. Drug Interactions with Metformin: Metformin is primarily used to manage blood sugar levels in individuals with type 2 diabetes. It works by improving insulin sensitivity and decreasing glucose production in the liver. Importantly, metformin does not have a known significant interaction with hormonal contraceptives like Delian. Therefore, taking metformin should not affect the contraceptive effectiveness of Delian. However, it is always advisable to inform your healthcare provider about all medications you are taking to ensure comprehensive care and monitoring.

2. Effectiveness of Delian: Regarding the effectiveness of Delian, it is crucial to understand how the pill works. When starting a new pack of Delian, it is generally recommended to take the first seven pills consistently for the first week to ensure maximum contraceptive effectiveness. This is particularly important if you are starting the pill for the first time or if you have not taken it for a while. The reason for this is that it takes time for the hormones in the pill to build up in your system and effectively suppress ovulation.

If you take the first pill of the new pack, it does not provide immediate contraceptive protection. The first seven days are considered a critical period where additional contraceptive methods (like condoms) should be used to prevent unintended pregnancy. After this initial period, if you have taken the pills correctly (i.e., at the same time every day without missing any doses), you can rely on Delian for contraceptive protection.

3. General Considerations: It’s also important to note that certain medications, particularly some antibiotics and anticonvulsants, can interfere with the effectiveness of hormonal contraceptives. However, as mentioned earlier, metformin does not fall into this category. Additionally, lifestyle factors such as gastrointestinal issues (vomiting or diarrhea) can also affect the absorption of the pill and its effectiveness.

4. Consultation with Healthcare Providers: If you have any concerns about drug interactions or the effectiveness of your birth control method, it is always best to consult with your healthcare provider. They can provide personalized advice based on your medical history and current medications.

In summary, taking metformin does not affect the effectiveness of Delian birth control pills. However, it is essential to take the first seven pills consistently to ensure contraceptive protection. Always consult with your healthcare provider for tailored advice and to address any concerns regarding your medications and contraceptive methods.

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