How to Confirm Chronic Gonorrhea: Symptoms and Diagnosis - Urology

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How is chronic gonorrhea diagnosed?


Hello doctor, I noticed pain during urination and discharge in early May.
After testing, I was diagnosed with gonorrhea.
The doctor prescribed a week’s worth of medication, which helped a lot, and the follow-up test results came back normal.
However, three days later, the pain during urination returned, and the tests indicated a recurrence.
I was prescribed medication again for seven days, but I still had discharge.
During my visit, I received a self-paid third-generation injection, and the next day the discharge disappeared.
Now I have persistent low urine output and occasional sharp pain in my lower back.
Could this be a progression to chronic gonorrhea?

A Du, 40~49 year old female. Ask Date: 2020/06/01

Dr. Du Shixi reply Urology


Hello: 1) The current official diagnostic method, in addition to relying on clinical symptoms and signs, requires the collection of specimens from the urethra, cervical canal, anus, rectum, and pharynx to perform Gram staining to identify Neisseria gonorrhoeae.
It is best to use selective culture media, such as Thayer-Martin agar, incubated in a carbon dioxide environment, followed by various biochemical or fluorescent antibody methods to confirm the diagnosis, as well as to identify the bacterial strain and conduct antibiotic susceptibility testing.
If a diagnosis is confirmed, it must be reported to the Centers for Disease Control.
2) It is difficult to say whether it has progressed to a chronic stage, but gonorrhea is not difficult to treat.
Lifestyle modifications are important; treatment should not rely solely on antibiotics.
For more information, please refer to https://www.cdc.gov.tw/File/Get/1qBP9dhsIpua_eQ99YooTg.

Reply Date: 2020/06/01

More Info


Chronic gonorrhea can be a challenging condition to diagnose and manage, especially if symptoms persist despite treatment. Gonorrhea is caused by the bacterium Neisseria gonorrhoeae, and while it is often treatable with antibiotics, complications can arise if the infection is not fully resolved.
In your case, it seems that you initially received treatment for gonorrhea, which improved your symptoms temporarily. However, the recurrence of pain during urination and the presence of discharge suggest that the infection may not have been completely eradicated. Chronic gonorrhea can occur when the infection persists for an extended period, often due to inadequate treatment or antibiotic resistance.

To confirm whether you have chronic gonorrhea, the following steps are typically recommended:
1. Symptom Assessment: Persistent symptoms such as painful urination, discharge, and lower abdominal pain can indicate that the infection is still present or has recurred. It is essential to keep track of these symptoms and report them to your healthcare provider.

2. Laboratory Testing: A repeat test for gonorrhea is crucial. This can be done through a urine test or a swab from the affected area (urethra, throat, or rectum, depending on the exposure). The test will help determine if Neisseria gonorrhoeae is still present.
3. Antibiotic Resistance Testing: If gonorrhea is confirmed, it is essential to check for antibiotic resistance. Some strains of Neisseria gonorrhoeae have developed resistance to commonly used antibiotics, which can lead to treatment failure. Your healthcare provider may recommend a culture test to identify the specific strain and its sensitivity to various antibiotics.

4. Follow-Up Care: If you are diagnosed with chronic gonorrhea or if the infection recurs, your healthcare provider may prescribe a different antibiotic regimen. It is crucial to complete the entire course of antibiotics as prescribed, even if symptoms improve before finishing the medication.

5. Partner Notification and Treatment: Gonorrhea is a sexually transmitted infection (STI), and it is essential to inform any sexual partners so they can also be tested and treated if necessary. This step helps prevent reinfection and further spread of the disease.

6. Consideration of Other STIs: Since gonorrhea often co-occurs with other STIs, it may be beneficial to get tested for other infections, such as chlamydia, syphilis, and HIV.
7. Monitoring for Complications: Chronic gonorrhea can lead to complications such as pelvic inflammatory disease (PID) in women, which can cause long-term reproductive health issues. If you experience severe symptoms like fever, severe abdominal pain, or unusual discharge, seek immediate medical attention.

In summary, to confirm chronic gonorrhea, it is essential to undergo repeat testing and possibly antibiotic resistance testing. Persistent symptoms warrant a thorough evaluation by a healthcare provider, who can guide you through the appropriate diagnostic and treatment steps. It is crucial to maintain open communication with your healthcare provider and follow their recommendations closely to ensure effective management of your condition.

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